Evidence map›Paper›PMID 30610105›Full record

ArticleMolecular cancer research : MCR2019

Reactive Oxygen Species (ROS)-Inducing Triterpenoid Inhibits Rhabdomyosarcoma Cell and Tumor Growth through Targeting Sp Transcription Factors.

Ravi Kasiappan, Indira Jutooru, Kumaravel Mohankumar, Keshav Karki, Alexandra Lacey, Stephen Safe

Open access · bronzeAbstract read
In one paragraph

Article in Molecular cancer research : MCR, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Specificity Proteins (Sp) and Cancer.International journal of molecular sciences · 2023
    Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Plants (Basel, Switzerland) · 2021
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Ravi KasiappanDepartment of Biochemistry, CSIR-Central Food Technological Research Institute, Mysore, Karnataka, India.ORCID 0000-0002-5351-9098
Indira JutooruDepartment of Veterinary Physiology and Pharmacology, Texas A&M University, College Station, Texas.
Kumaravel MohankumarDepartment of Veterinary Physiology and Pharmacology, Texas A&M University, College Station, Texas.
Keshav KarkiDepartment of Veterinary Physiology and Pharmacology, Texas A&M University, College Station, Texas.
Alexandra LaceyDepartment of Veterinary Physiology and Pharmacology, Texas A&M University, College Station, Texas.
Stephen SafeDepartment of Veterinary Physiology and Pharmacology, Texas A&M University, College Station, Texas. ssafe@cvm.tamu.edu.ORCID 0000-0002-2115-3060
Texas A&M University · USCentral Food Technological Research Institute · IN

Funding

Texas A&M Center for Environmental Health Research (TiCER)P30ES029067 · NIEHS · TEXAS A&M UNIVERSITY · PI Galen Newman · 2019 to 2026
$13.0M
Regulatory Science in Environmental Health and ToxicologyT32ES026568 · NIEHS · TEXAS A&M UNIVERSITY · PI Weihsueh A Chiu, Natalie M Johnson · 2016 to 2026
$3.8M
TARGETED GENOMICS FACILITY COREP30ES023512 · NIEHS · TEXAS A&M AGRILIFE RESEARCH · PI THREADGILL, DAVID W. · 2014 to 2017
$3.3M
NIEHS NIH HHS P30 ES023512NIEHS NIH HHS P30 ES029067NIEHS NIH HHS T32 ES026568
6 · The paper itself

Abstract

Methyl 2-trifluoromethyl-3,11-dioxo-18β-olean-1,12-dien-3-oate (CF

Indexed as

AnimalsCell Line, TumorCell ProliferationFemaleHumansMiceMice, NudeReactive Oxygen SpeciesRhabdomyosarcomaSp Transcription FactorsTransfectionTriterpenesReactive Oxygen SpeciesSp Transcription FactorsTriterpenestriterpenoid TP-222

Identifiers

PMID30610105
PMCPMC6397684
OpenAlexW2908405893

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.