Evidence map›Paper›PMID 30610097›Full record

ArticleNeurology2019

Adherence with psychotherapy and treatment outcomes for psychogenic nonepileptic seizures.

Benjamin Tolchin, Barbara A Dworetzky, Steve Martino, Hal Blumenfeld, Lawrence J Hirsch, Gaston Baslet

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 45 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Benjamin TolchinFrom the Comprehensive Epilepsy Center, Department of Neurology (B.T., H.B., L.J.H.), and Department of Psychiatry (S.M.), Yale University School of Medicine, New Haven, CT; Epilepsy Center of Excellence, Neurology Service (B.T.), and Psychology Service (S.M.), VA Connecticut Healthcare System, Newington; and Departments of Neurology (B.T., B.A.D.) and Psychiatry (G.B.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA. benjamin.tolchin@yale.edu.ORCID 0000-0002-9099-0022
Barbara A DworetzkyFrom the Comprehensive Epilepsy Center, Department of Neurology (B.T., H.B., L.J.H.), and Department of Psychiatry (S.M.), Yale University School of Medicine, New Haven, CT; Epilepsy Center of Excellence, Neurology Service (B.T.), and Psychology Service (S.M.), VA Connecticut Healthcare System, Newington; and Departments of Neurology (B.T., B.A.D.) and Psychiatry (G.B.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Steve MartinoFrom the Comprehensive Epilepsy Center, Department of Neurology (B.T., H.B., L.J.H.), and Department of Psychiatry (S.M.), Yale University School of Medicine, New Haven, CT; Epilepsy Center of Excellence, Neurology Service (B.T.), and Psychology Service (S.M.), VA Connecticut Healthcare System, Newington; and Departments of Neurology (B.T., B.A.D.) and Psychiatry (G.B.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Hal BlumenfeldFrom the Comprehensive Epilepsy Center, Department of Neurology (B.T., H.B., L.J.H.), and Department of Psychiatry (S.M.), Yale University School of Medicine, New Haven, CT; Epilepsy Center of Excellence, Neurology Service (B.T.), and Psychology Service (S.M.), VA Connecticut Healthcare System, Newington; and Departments of Neurology (B.T., B.A.D.) and Psychiatry (G.B.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Lawrence J HirschFrom the Comprehensive Epilepsy Center, Department of Neurology (B.T., H.B., L.J.H.), and Department of Psychiatry (S.M.), Yale University School of Medicine, New Haven, CT; Epilepsy Center of Excellence, Neurology Service (B.T.), and Psychology Service (S.M.), VA Connecticut Healthcare System, Newington; and Departments of Neurology (B.T., B.A.D.) and Psychiatry (G.B.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Gaston BasletFrom the Comprehensive Epilepsy Center, Department of Neurology (B.T., H.B., L.J.H.), and Department of Psychiatry (S.M.), Yale University School of Medicine, New Haven, CT; Epilepsy Center of Excellence, Neurology Service (B.T.), and Psychology Service (S.M.), VA Connecticut Healthcare System, Newington; and Departments of Neurology (B.T., B.A.D.) and Psychiatry (G.B.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Brigham and Women's Hospital · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
6 · The paper itself

Abstract

objectiveWe conducted a prospective cohort study of patients with psychogenic nonepileptic seizures (PNES) to examine the association between adherence with psychotherapy and outcomes, including significant (≥50%) reduction in PNES frequency, PNES freedom, improvement in quality of life, and reduction in emergency department (ED) utilization.

methodsA total of 105 participants were referred to receive psychotherapy either at Brigham and Women's Hospital or with a local therapist. We called participants at 12-24 months follow-up and obtained detailed follow-up data from 93 participants (89%). Participants were considered adherent with psychotherapy if they attended at least 8 sessions within a 16-week period starting at the time of referral.

resultsAdherence with psychotherapy was associated with reduction in seizure frequency (84% in adherent group vs 61% in nonadherent,

conclusionsOur study is limited in that it cannot establish a causal relationship between adherence with psychotherapy and outcomes, and the results may not generalize beyond the single quaternary care center study site. Among participants with documented PNES, adherence with psychotherapy was associated with reduction in PNES frequency, improvement in quality of life, and decrease in ED visits.

Indexed as

PsychotherapyQuality of LifeAdolescentAdultAdult Survivors of Child AbuseAgedAged, 80 and overCohort StudiesConversion DisorderEmergency Service, HospitalEthnicityFemaleFollow-Up StudiesHumansMaleMiddle Aged

Identifiers

PMID30610097
PMCPMC6382361
OpenAlexW2908450279

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.