Evidence map›Paper›PMID 30609948›Full record

ArticleJournal of the American Association for Laboratory Animal Science : JAALAS2019

Evaluation of 4 Presurgical Skin Preparation Methods in Mice.

Brenda L Kick, Sanjeev Gumber, Heqiong Wang, Reneé H Moore, Douglas K Taylor

Abstract readClinical Trial, Veterinary
In one paragraph

Article in Journal of the American Association for Laboratory Animal Science : JAALAS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Ovariectomy/Orchidectomy in Rodents.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  3. Article
  4. Article
  5. An Experimental Model of Proton-Beam-Induced Radiation Dermatitis In Vivo.International journal of molecular sciences · 2023
    Article
  6. Review
  7. Article
  8. Article
  9. The Use of Waterless Alcohol-based Antiseptic for Surgical Skin Preparation in Rhesus Macaques (Journal of the American Association for Laboratory Animal Science : JAALAS · 2022
    Article
  10. Assessment of 2 Hair Removal Methods in New Zealand White Rabbits (Journal of the American Association for Laboratory Animal Science : JAALAS · 2022
    Article
  11. Article
  12. Using Waterless Alcohol-based Antiseptic for Skin Preparation and Active Thermal Support in Laboratory Rats.Journal of the American Association for Laboratory Animal Science : JAALAS · 2021
    Article
  13. Comparison of Two Hair Removal Methods in Sprague-Dawley Rats (Journal of the American Association for Laboratory Animal Science : JAALAS · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Brenda L KickDivision of Animal Resources, Emory University, Atlanta, Georgia;, Email: bkick86@gmail.com.
Sanjeev GumberDivision of Pathology, Yerkes National Primate Research Center, Atlanta, Georgia, Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia.
Heqiong WangDepartment of Biostatistics and Bioinformatics, Emory University School of Public Health, Emory University, Atlanta, Georgia.
Reneé H MooreDepartment of Biostatistics and Bioinformatics, Emory University School of Public Health, Emory University, Atlanta, Georgia.
Douglas K TaylorDivision of Animal Resources, Emory University, Atlanta, Georgia, Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia.
Emory University · US

Funding

Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0M
NIH HHS P51 OD011132
6 · The paper itself

Abstract

Mice routinely undergo surgical procedures for use in research; however, studies of skin preparation methods to achieve antisepsis are rare. The present study evaluated 4 skin preparation treatments: depilatory agent followed by povidone-iodine and alcohol scrub; depilatory agent followed by povidone-iodine and saline scrub; electric clippers followed by povidone-iodine and alcohol scrub; and electric clippers followed by povidone-iodine and saline scrub. Swabs for bacterial culture were obtained immediately after hair removal and after scrubbing to measure the reduction in bacterial load. Full-thickness incisions were assigned ASEPSIS wound scores and examined histologically on days 0, 1, and 7 after surgery. Neither bacterial load growth nor ASEPSIS wound scores differed among any of the treatments. Histopathology revealed statistically significant but biologically irrelevant differences. Overall all treatment methods achieved acceptable bacterial load reduction and surgical site healing.

Indexed as

ChlorhexidinePovidone-IodinePreoperative CareSurgical Wound InfectionAnimalsAnti-Infective Agents, LocalAsepsisEthanolMiceSkinAnti-Infective Agents, LocalChlorhexidineEthanolPovidone-Iodine

Identifiers

PMID30609948
PMCPMC6351048
OpenAlexW2907070503

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.