Evidence map›Paper›PMID 30609807›Full record

ArticleInternational journal of molecular sciences2019

MiR-125b-2 Knockout in Testis Is Associated with Targeting to the PAP Gene, Mitochondrial Copy Number, and Impaired Sperm Quality.

Longlong Li, Yanling Zhu, Ting Chen, Jiajie Sun, Junyi Luo, Gang Shu, Songbo Wang, Xiaotong Zhu, Qingyan Jiang, Yongliang Zhang and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Protection byPharmaceuticals (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Longlong LiGuangdong Provincial Key Laboratory of Animal Nutrition Control, College of Animal Science, South China Agricultural University, Guangzhou 510642, China. longlongli0607@163.com.
Yanling ZhuGuangdong Provincial Key Laboratory of Animal Nutrition Control, College of Animal Science, South China Agricultural University, Guangzhou 510642, China. kerryju27@163.com.
Ting ChenGuangdong Provincial Key Laboratory of Animal Nutrition Control, College of Animal Science, South China Agricultural University, Guangzhou 510642, China. allinchen@scan.edu.cn.
Jiajie SunGuangdong Provincial Key Laboratory of Animal Nutrition Control, College of Animal Science, South China Agricultural University, Guangzhou 510642, China. jiajiesun@scau.edu.cn.
Junyi LuoGuangdong Provincial Key Laboratory of Animal Nutrition Control, College of Animal Science, South China Agricultural University, Guangzhou 510642, China. luojunyi@scau.edu.cn.
Gang ShuGuangdong Provincial Key Laboratory of Animal Nutrition Control, College of Animal Science, South China Agricultural University, Guangzhou 510642, China. shugang@scau.edu.cn.
Songbo WangGuangdong Provincial Key Laboratory of Animal Nutrition Control, College of Animal Science, South China Agricultural University, Guangzhou 510642, China. songbowang@gmail.com.
Xiaotong ZhuGuangdong Provincial Key Laboratory of Animal Nutrition Control, College of Animal Science, South China Agricultural University, Guangzhou 510642, China. xtzhu@scau.edu.cn.
Qingyan JiangGuangdong Provincial Key Laboratory of Animal Nutrition Control, College of Animal Science, South China Agricultural University, Guangzhou 510642, China. qyjiang@scau.edu.cn.
Yongliang ZhangGuangdong Provincial Key Laboratory of Animal Nutrition Control, College of Animal Science, South China Agricultural University, Guangzhou 510642, China. zhangyl@scau.edu.cn.
Qianyun XiGuangdong Provincial Key Laboratory of Animal Nutrition Control, College of Animal Science, South China Agricultural University, Guangzhou 510642, China. xqy0228@163.com.
South China Agricultural University · CN

Funding

National Key Research and Development Program of China 2016YFD0501205, 2016YFD0500503Natural Science Foundation of China program 31872435 and 31472163The Key Project of Guangdong Provincial Nature Science Foundation 2018B030311015, 2016A030313413
6 · The paper itself

Abstract

It has been reported that the miR-125 family plays an important role in regulating embryo development. However, the function of miR-125b-2 in spermatogenesis remains unknown. In this study, we used a model of miR-125b knockout (KO) mice to study the relationship between miR-125b-2 and spermatogenesis. Among the KO mice, the progeny test showed that the litter size decreased significantly (

Indexed as

3' Untranslated RegionsAnimalsDNA Copy Number VariationsDNA, MitochondrialFemaleGerm CellsMaleMiceMice, KnockoutMicroRNAsMitochondriaPancreatitis-Associated ProteinsSpermatogenesisSpermatozoaTestisTestosterone3' Untranslated RegionsDNA, MitochondrialMicroRNAsMirn125 microRNA, mousePancreatitis-Associated ProteinsReg3b protein, mouseTestosteronemiR-125b-2mitochondriaPAPreproductionspermtestis

Identifiers

PMID30609807
PMCPMC6337273
OpenAlexW2901893027

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.