ReviewNutrients2019
Elemental Metabolomics and Pregnancy Outcomes.
Review in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 61 citations in OpenAlex.
- Optimisation of Micronutrient Supplementation During Pregnancy: Interactions Between Bioactive Compounds, Their Impact on Health, and Regulatory Considerations.Biomolecules · 2026Review
- Systems biology insights into the molecular drivers of childhood stunting and implications for intervention.Frontiers in nutrition · 2026Review
- Associations of Heavy Metals and Trace Elements with Gestational Diabetes Mellitus in the Boston Birth Cohort.Environmental science & technology · 2025Article
- Evaluating the Chorioretinal Microcirculation in Preeclampsia with OCT-Angiography: A Narrative Literature Review.Journal of clinical medicine · 2025Review
- Heme oxygenase/carbon monoxide system affects the placenta and preeclampsia.Medical gas research · 2025Review
- Lipidomic Signature of Pregnant and Postpartum Females by Longitudinal and Transversal Evaluation: Putative Biomarkers Determined by UHPLC-QTOF-ESIMetabolites · 2025Article
- Advancement in predictive biomarkers for gestational diabetes mellitus diagnosis and related outcomes: a scoping review.BMJ open · 2024Article
- Article
- Assessment of Maternal Retinal Microvasculature in Preterm Pregnancy Using OCT-Angiography: a Cross-Sectional Study.Maedica · 2023Article
- Impact of Selected Eicosanoids in Normal and Pathological Pregnancies.Journal of clinical medicine · 2023Article
- Does the Micronutrient Molybdenum Have a Role in Gestational Complications and Placental Health?Nutrients · 2023Review
- Associations of maternal plasma and umbilical cord plasma metabolomics profiles with birth anthropometric measures.Pediatric research · 2023Article
- Downregulation of argininosuccinate synthase 1 (ASS1) is associated with hypoxia in placental development.Human cell · 2023Article
- Effects of Non-Essential "Toxic" Trace Elements on Pregnancy Outcomes: A Narrative Overview of Recent Literature Syntheses.International journal of environmental research and public health · 2023Review
- Utilizing Amniotic Fluid Metabolomics to Monitor Fetal Well-Being: A Narrative Review of the Literature.Cureus · 2023Review
- Calcium, Potassium, Sodium, and Magnesium Concentrations in the Placenta, Umbilical Cord, and Fetal Membrane from Women with Multiple Pregnancies.Life (Basel, Switzerland) · 2023Article
- Immune System and Psychological State of Pregnant Women during COVID-19 Pandemic: Are Micronutrients Able to Support Pregnancy?Nutrients · 2022Review
- Selected Metal Concentration in Maternal and Cord Blood.International journal of environmental research and public health · 2021Article
- Circulating trace elements for the prediction of preeclampsia and small for gestational age babies.Metabolomics : Official journal of the Metabolomic Society · 2021Article
- Trace Element Analysis in Whole Blood and Plasma for Reference Levels in a Selected Queensland Population, Australia.International journal of environmental research and public health · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Trace elements are important for human health and development. The body requires specific micronutrients to function, with aberrant changes associated with a variety of negative health outcomes. Despite this evidence, the status and function of micronutrients during pregnancy are relatively unknown and more information is required to ensure that women receive optimal intakes for foetal development. Changes in trace element status have been associated with pregnancy complications such as gestational diabetes mellitus (GDM), pre-eclampsia (PE), intrauterine growth restriction (IUGR), and preterm birth. Measuring micronutrients with methodologies such as elemental metabolomics, which involves the simultaneous quantification and characterisation of multiple elements, could provide insight into gestational disorders. Identifying unique and subtle micronutrient changes may highlight associated proteins that are affected underpinning the pathophysiology of these complications, leading to new means of disease diagnosis. This review will provide a comprehensive summary of micronutrient status during pregnancy, and their associations with gestational disorders. Furthermore, it will also comment on the potential use of elemental metabolomics as a technique for disease characterisation and prediction.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.