Evidence map›Paper›PMID 30608652›Full record

ArticleAnalytical chemistry2019

Real-Time Pure Shift HSQC NMR for Untargeted Metabolomics.

István Timári, Cheng Wang, Alexandar L Hansen, Gilson Costa Dos Santos, Sung Ok Yoon, Lei Bruschweiler-Li, Rafael Brüschweiler

Abstract read
In one paragraph

Article in Analytical chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. NMR methods for the analysis of mixtures.Chemical communications (Cambridge, England) · 2022
    Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

István Timári
Cheng Wang
Alexandar L Hansen
Gilson Costa Dos Santos
Sung Ok Yoon
Lei Bruschweiler-Li
Rafael BrüschweilerORCID 0000-0003-3649-4543

Funding

Preclinical drug development of isoform selective JNK3 inhibitors for Alzheimer's disease.R01AG055059 · NIA · OHIO STATE UNIVERSITY · PI FENG, YANGBO, YOON, SUNG OK · 2017 to 2021
$4.2M
New hybrid methods for the improved and integrated analysis of complex metabolomics mixturesR01GM066041 · NIGMS · OHIO STATE UNIVERSITY · PI BRUSCHWEILER, RAFAEL · 2002 to 2019
$3.3M
NIA NIH HHS R01 AG055059NIGMS NIH HHS R01 GM066041
6 · The paper itself

Abstract

Sensitivity and resolution are key considerations for NMR applications in general and for metabolomics in particular, where complex mixtures containing hundreds of metabolites over a large range of concentrations are commonly encountered. There is a strong demand for advanced methods that can provide maximal information in the shortest possible time frame. Here, we present the optimization and application of the recently introduced 2D real-time BIRD

Indexed as

MetabolomeAnimalsMetabolomicsMiceNuclear Magnetic Resonance, BiomolecularUrine

Identifiers

PMID30608652
PMCPMC6386528

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.