ArticleAnalytical chemistry2019
Extending the Scope of
Article in Analytical chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 29 citations in OpenAlex.
- Identification and Distribution of the Dietary Antioxidant Ergothioneine in Humans and Animal Models Combining NMR, RANSY, and MS Methods.Analytical chemistry · 2025Article
- Discovery of Hypoxanthine and Inosine as Robust Biomarkers for Predicting the Preanalytical Quality of Human Plasma and Serum for Metabolomics.Analytical chemistry · 2024Article
- Determination of fatty acid uptake and desaturase activity in mammalian cells by NMR-based stable isotope tracing.Analytica chimica acta · 2024Article
- Intracellular pyruvate-lactate-alanine cycling detected using real-time nuclear magnetic resonance spectroscopy of live cells and isolated mitochondria.Magnetic resonance in chemistry : MRC · 2024Article
- Monitoring live mitochondrial metabolism in real-time using NMR spectroscopy.Magnetic resonance in chemistry : MRC · 2023Article
- Multi-Method Quantification of Acetyl-Coenzyme A and Further Acyl-Coenzyme A Species in Normal and Ischemic Rat Liver.International journal of molecular sciences · 2023Article
- Anomalous Dynamics of Labile Metabolites in Cold Human Blood Detected UsingAnalytical chemistry · 2023Article
- Whole Body Distribution of Labile Coenzymes and Antioxidants in a Mouse Model as Visualized UsingAnalytical chemistry · 2023Article
- NMR Metabolomics Methods for Investigating Disease.Analytical chemistry · 2023Review
- Quantitative NMR Methods in Metabolomics.Handbook of experimental pharmacology · 2023Article
- NMR as a readout to monitor and restore the integrity of complex chemoenzymatic reactions.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2022Article
- NMR-Based Metabolomics.Advances in experimental medicine and biology · 2021Article
- Mitochondrial electron transport chain: Oxidative phosphorylation, oxidant production, and methods of measurement.Redox biology · 2020Review
- Analysis of Coenzymes and Antioxidants in Tissue and Blood Using 1DMethods in molecular biology (Clifton, N.J.) · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Coenzyme A (CoA) and acetyl-coenzyme A (acetyl-CoA) are ubiquitous cellular molecules, which mediate hundreds of anabolic and catabolic reactions including energy metabolism. Highly sensitive methods including absorption spectroscopy and mass spectrometry enable their analysis, albeit with many limitations. To date, however, NMR spectroscopy has not been used to analyze these important molecules. Building on our recent efforts, which enabled simultaneous analysis of a large number of metabolites in tissue and blood including many coenzymes and antioxidants ( Anal. Chem. 2016, 88, 4817-24; ibid 2017, 89, 4620-4627), we describe here a new method for identification and quantitation of CoA and acetyl-CoA ex vivo in tissue. Using mouse heart, kidney, liver, brain, and skeletal tissue, we show that a simple
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.