ArticleNucleic acids research1988
Isolation of human cDNA clones of myb-related genes, A-myb and B-myb.
Article in Nucleic acids research, 1988. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 93 papers.
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Who cites it
93 citing papers in PubMed.
- From modulation of cellular plasticity to potentiation of therapeutic resistance: new and emerging roles of MYB transcription factors in human malignancies.Cancer metastasis reviews · 2024Review
- RAD gene family analysis in cotton provides some key genes for flowering and stress tolerance in upland cotton G. hirsutum.BMC genomics · 2022Article
- B-Myb accelerates colorectal cancer progression through reciprocal feed-forward transactivation of E2F2.Oncogene · 2021Article
- MYB oncoproteins: emerging players and potential therapeutic targets in human cancer.Oncogenesis · 2021Review
- The cell cycle regulatory DREAM complex is disrupted by high expression of oncogenic B-Myb.Oncogene · 2019Article
- c-MYB and DMTF1 in Cancer.Cancer investigation · 2019Review
- MYCN is amplified during S phase, and c‑myb is involved in controlling MYCN expression and amplification in MYCN‑amplified neuroblastoma cell lines.Molecular medicine reports · 2019Article
- Evolution of RAD- and DIV-Like Genes in Plants.International journal of molecular sciences · 2017Article
- MYBL2 (B-Myb): a central regulator of cell proliferation, cell survival and differentiation involved in tumorigenesis.Cell death & disease · 2017Review
- Parallel Regulation of von Hippel-Lindau Disease by pVHL-Mediated Degradation of B-Myb and Hypoxia-Inducible Factor α.Molecular and cellular biology · 2016Article
- Novel Molecular Markers for Breast Cancer.Biomarkers in cancer · 2016Review
- Early Evolution of Vertebrate Mybs: An Integrative Perspective Combining Synteny, Phylogenetic, and Gene Expression Analyses.Genome biology and evolution · 2015Article
- Role of Cdk1 in DNA damage-induced G1 checkpoint abrogation by the human papillomavirus E7 oncogene.Cell cycle (Georgetown, Tex.) · 2014Article
- B-myb is a gene implicated in cell cycle and proliferation of breast cancer.International journal of clinical and experimental pathology · 2014Article
- The complex containing Drosophila Myb and RB/E2F2 regulates cytokinesis in a histone H2Av-dependent manner.Molecular and cellular biology · 2013Article
- Duplication and maintenance of the Myb genes of vertebrate animals.Biology open · 2013Article
- A chemical screen identifies the chemotherapeutic drug topotecan as a specific inhibitor of the B-MYB/MYCN axis in neuroblastoma.Oncotarget · 2012Article
- Article
- Novel chromosomal rearrangements and break points at the t(6;9) in salivary adenoid cystic carcinoma: association with MYB-NFIB chimeric fusion, MYB expression, and clinical outcome.Clinical cancer research : an official journal of the American Association for Cancer Research · 2011Article
- Mybl2, downregulated during colon epithelial cell maturation, is suppressed by miR-365.American journal of physiology. Gastrointestinal and liver physiology · 2011Article
33 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
cDNA clones of the myb-related genes A-myb and B-myb were obtained by screening human cDNA libraries. The predicted open reading frame of B-myb could encode a protein of 700 amino acid residues. Although the C-terminal end has not been cloned yet, an almost entire coding region of A-myb, which is 745 amino acid long, was determined. The A-myb and B-myb proteins are highly homologous with the myb protein in three regions. Domain I, which is 161 amino acid long, is well conserved in the myb gene family. The homology between human-myb and A-myb in domain I is 90% at the amino acid level. Domain II, which is about 85 amino acid long, is less well conserved. Although it is a short stretch, domain III is found in the C-terminal region. The mRNAs of A-myb and B-myb were 5.0 and 2.6 kb, respectively. The mRNA expression pattern of the myb gene family in various tumors is presented.
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