ArticleThe Journal of head trauma rehabilitation
Prevalence of Medical and Psychiatric Comorbidities Following Traumatic Brain Injury.
Article in The Journal of head trauma rehabilitation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 2 of them syntheses that pooled it.
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Who cites it
69 citing papers in PubMed, 2 syntheses or guidelines pooled it, 142 citations in OpenAlex.
- Group Psychosocial Interventions Following Acquired Brain Injury: A Systematic Review and Meta-analysis of Group Process and Outcomes.Neuropsychology review · 2026Pooled it
- Comorbidity in traumatic brain injury and functional outcomes: a systematic review.European journal of physical and rehabilitation medicine · 2021Pooled it
- Collaborative Care for Chronic Pain After Traumatic Brain Injury: A Randomized Clinical Trial.JAMA network open · 2024Trial
- Sex and Gender Differences in Physical Activity, Sedentary Behavior, and Sleep During Traumatic Brain Injury Recovery: A Narrative Review.European journal of sport science · 2026Review
- Psilocybin restores behavior and 5-HTCell reports. Medicine · 2026Article
- Life satisfaction trajectories over the 10 years post-TBI among Asian Americans and Pacific Islanders: A model systems study.Rehabilitation psychology · 2026Article
- The normative modelling framework for traumatic brain injury.Brain : a journal of neurology · 2025Review
- Evaluation of Traumatic Brain Injury Severity Using the Abbreviated Injury Scale and the Injury Severity Score: A Retrospective Study in Two Eastern European Centers.Journal of clinical medicine · 2025Article
- The burden of somatic comorbidities in patients surviving a traumatic brain injury.Acta neurochirurgica · 2025Article
- Vascular Risk Factors and 1-Year Cognitive Change Among Individuals With Traumatic Brain Injury.JAMA network open · 2025Article
- Exploring comorbidity networks in mild traumatic brain injury subjects through graph theory: a traumatic brain injury model systems study.BMC neurology · 2025Article
- Extracranial Effects of Traumatic Brain Injury: A Narrative Review.Clinics and practice · 2025Review
- Metabolic disorders after traumatic brain injury: a narrative review of systemic consequences.Metabolic brain disease · 2025Review
- Article
- Traumatic Brain Injury and Risk of Incident Comorbidities.JAMA network open · 2024Article
- Review
- Characterizing a Common Phenomenon: Why do Trauma Patients Re-present to the Emergency Department?The Journal of surgical research · 2024Article
- Increased Risk for Clinically Significant Sleep Disturbances in Mild Traumatic Brain Injury: An Approach to Leveraging the Federal Interagency Traumatic Brain Injury Research Database.Brain sciences · 2024Article
- Article
- Cerebral hypoperfusion exacerbates traumatic brain injury in male but not female mice.The European journal of neuroscience · 2024Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 2 countries.
Funding
Abstract
objectiveTo examine the prevalence of selected medical and psychiatric comorbidities that existed prior to or up to 10 years following traumatic brain injury (TBI) requiring acute rehabilitation.
designRetrospective cohort.
settingSix TBI Model Systems (TBIMS) centers.
participantsIn total, 404 participants in the TBIMS National Database who experienced TBI 10 years prior.
interventionsNot applicable.
main outcome measureSelf-reported medical and psychiatric comorbidities and the onset time of each endorsed comorbidity.
resultsAt 10 years postinjury, the most common comorbidities developing postinjury, in order, were back pain, depression, hypertension, anxiety, fractures, high blood cholesterol, sleep disorders, panic attacks, osteoarthritis, and diabetes. Comparing those 50 years and older to those younger than 50 years, diabetes (odds ratio [OR] = 3.54; P = .0016), high blood cholesterol (OR = 2.04; P = .0092), osteoarthritis (OR = 2.02; P = .0454), and hypertension (OR = 1.84; P = .0175) were significantly more prevalent in the older cohort while panic attacks (OR = 0.33; P = .0022) were significantly more prevalent in the younger cohort. No significant differences in prevalence rates between the older and younger cohorts were found for back pain, depression, anxiety, fractures, or sleep disorders.
conclusionsPeople with moderate-severe TBI experience other medical and mental health comorbidities during the long-term course of recovery and life after injury. The findings can inform further investigation into comorbidities associated with TBI and the role of medical care, surveillance, prevention, lifestyle, and healthy behaviors in potentially modifying their presence and/or prevalence over the life span.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.