ArticleDermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]2019
Squamous Cell Carcinoma in Perineal, Perianal, and Gluteal Hidradenitis Suppurativa: Experience in 12 Patients.
Article in Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Mohs Micrographic Surgery Versus Wide Local Excision in the Treatment of Anogenital Squamous Cell Carcinoma: A Systematic Review.International journal of dermatology · 2025Pooled it
- A state-of-the-art systematic review of cancer in hidradenitis suppurativa.Annals of medicine · 2024Pooled it
- Revisiting Radiotherapy for Hidradenitis Suppurativa: Clinical Outcomes, Safety, and Optimization Strategies: A Systematic Review.Journal of clinical medicine · 2026Review
- HPV-16-Induced Squamous Cell Carcinoma in Hidradenitis Suppurativa: HPV Vaccination May Be Useful.Cancers · 2025Article
- Multiple verrucous squamous cell carcinomas developing on chronic hidradenitis suppurativa lesions-a rare case report from Romania.Frontiers in medicine · 2024Article
- Hidradenitis suppurativa and squamous cell carcinoma: a systematic review of the literature.Postepy dermatologii i alergologii · 2023Review
- A rare case of axillary keratoacanthoma arising in hidradenitis suppurativa.JAAD case reports · 2022Article
- Male Perineal Carcinoma: Experience in 4 Cases and Literature Review.Case reports in urology · 2022Article
- Neoplastic Implications in Patients Suffering from Hidradenitis Suppurativa under Systemic Treatments.Biomedicines · 2021Review
- Vulval squamous cell carcinoma arising from hidradenitis suppurrativa.BMJ case reports · 2021Article
- Article
- [Hidradenitis suppurativa/acne inversa in the genitoanal region].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2020Review
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5 authors at 3 institutions in 1 country.
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Abstract
backgroundFew reports describe squamous cell carcinoma (SCC) arising in hidradenitis suppurativa (HS).
objectiveThe 2 objectives were (1) to describe the clinical characteristics, pathologic findings, and postoperative outcomes of SCC in HS and (2) to assess whether human papillomavirus (HPV) is involved in the pathogenesis. MATERIALS AND
methodsCases of SCC in HS were identified through institutional medical records (1976-2013) and the Rochester Epidemiology Project. Tumor specimens were assessed for HPV DNA/RNA with in situ hybridization.
resultsTwelve patients were identified (11 Caucasians and 9 men). All SCCs involved gluteal, perianal, or perineal skin; 1 patient had, in addition, involvement of the vagina. Surgical excision was performed on all 12 patients, 4 of whom had a colostomy. Mean duration of HS before SCC development was 28.5 years (range, 15-53 years). Mean follow-up was 4.3 years after surgical excision. Seven of 12 patients followed had postoperative SCC recurrence. Squamous cell carcinoma caused death despite wide surgical excision in these 7 patients. Of the remaining 5 patients, 4 are unknown and 1 who did not recur had an in situ SCC (Bowen disease carcinoma). Squamous cell carcinoma was not associated with high-risk or low-risk HPV.
conclusionInvasive SCC arising in HS carries a high risk of death.
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