ArticleJournal of the American Heart Association2018
Rapid Systolic Blood Pressure Changes After Standing Up Associate With Impaired Physical Performance in Geriatric Outpatients.
Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Prevalence of initial orthostatic hypotension in older adults: a systematic review and meta-analysis.Age and ageing · 2021Pooled it
- A Closed-Loop Cardiovascular Model of the Supine-To-Stand Manoeuvre: Implications for Falls.International journal for numerical methods in biomedical engineering · 2026Article
- Prevalence of initial orthostatic hypotension in geriatric inpatients: the role of time to stand.European geriatric medicine · 2026Article
- Exploring the relationship between orthostatic hypotension and gait in people with Parkinson's disease.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2025Article
- Relationship Between the Drop Rate of Standing Blood Pressure and Major Adverse Cardiovascular Events.Journal of clinical hypertension (Greenwich, Conn.) · 2025Article
- The relationship between comorbidities, physical inactivity, kinesiophobia and physical performance in hypertensive individuals: a cross-sectional study.BMC cardiovascular disorders · 2025Article
- Cardiovascular Autonomic Function and Progression of Age-Related Macular Degeneration in The Irish Longitudinal Study of Ageing (TILDA).Investigative ophthalmology & visual science · 2024Article
- Slower speed of blood pressure recovery after standing is associated with accelerated brain aging: Evidence from The Irish Longitudinal Study on Ageing (TILDA).Cerebral circulation - cognition and behavior · 2024Article
- Differential Associations Between Two Markers of Probable Sarcopenia and Continuous Orthostatic Hemodynamics in The Irish Longitudinal Study on Ageing.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
- Central command suppresses pressor-evoked bradycardia at the onset of voluntary standing up in conscious cats.Experimental physiology · 2023Article
- Identifying the Optimal Parameters to Express the Capacity-Activity Interrelationship of Community-Dwelling Older Adults Using Wearable Sensors.Sensors (Basel, Switzerland) · 2022Article
- Impaired Stabilization of Orthostatic Cerebral Oxygenation Is Associated With Slower Gait Speed: Evidence From The Irish Longitudinal Study on Ageing.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022Article
- Feasibility of Diagnosing Initial Orthostatic Hypotension Using a Continuous Blood Pressure Device in Geriatric Rehabilitation Inpatients: RESORT.Gerontology · 2022Article
- Diagnostic criteria for initial orthostatic hypotension: a narrative review.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2021Review
- Initial orthostatic hypotension and orthostatic intolerance symptom prevalence in older adults: A systematic review.International Journal of Cardiology. Hypertension · 2021Review
- Malnutrition is associated with dynamic physical performance.Aging clinical and experimental research · 2020Article
- Blood Pressure Drop Rate After Standing Up Is Associated With Frailty and Number of Falls in Geriatric Outpatients.Journal of the American Heart Association · 2020Article
- Multimodal Monitoring of Cardiovascular Responses to Postural Changes.Frontiers in physiology · 2020Article
- Rapid Systolic Blood Pressure Changes After Standing Up Associate With Impaired Physical Performance in Geriatric Outpatients.Journal of the American Heart Association · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Orthostatic hypotension is a prevalent condition in older adults and is associated with impaired physical performance and falls. The ability of older adults to compensate for rapid changes in systolic blood pressure ( SBP ; ie, SBP decline rate and SBP variability) may be important for physical performance. This study investigates the association of rapid SBP changes after standing up with physical performance. Methods and Results Consecutive patients who visited the Center of Geriatrics Amsterdam in 2014 and 2015 were included. The following SBP parameters were computed in 2 intervals (0-15 and 15-180 seconds) after standing up: steepness of steepest SBP decline; ratio of standing/supine SBP variability; and magnitude of largest SBP decline. Physical performance was assessed using the following measures: chair stand time, timed up and go time, walking speed, handgrip strength, and tandem stance performance. A total of 109 patients (45% men; age, mean, 81.7 years [ standard deviation , 7.0 years]) were included. Steepness of steepest SBP decline (0-15 seconds) was associated with slower chair stand time ( P<0.001), timed up and go time ( P=0.022), and walking speed ( P=0.024). Ratio of standing/supine SBP variability (0-15 seconds) was associated with slower chair stand time ( P=0.005). Magnitude of largest SBP decline was not associated with physical performance. Conclusions SBP parameters reflecting rapid SBP changes were more strongly associated with physical performance compared with SBP decline magnitude in geriatric outpatients. These results support the hypothesis of an inadequate cerebral autoregulation during rapid SBP changes and advocate the use of continuous blood pressure measurements.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.