Evidence map›Paper›PMID 30608173›Full record

ArticleThe Journal of organic chemistry2019

Outer-Sphere Control for Divergent Multicatalysis with Common Catalytic Moieties.

Christopher R Shugrue, Bianca R Sculimbrene, Elizabeth R Jarvo, Brandon Q Mercado, Scott J Miller

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of organic chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. IUCrData · 2023
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Christopher R ShugrueDepartment of Chemistry , Yale University , P.O. Box 208107, New Haven , Connecticut 06520-8107 , United States.ORCID 0000-0002-3504-9475
Bianca R SculimbreneDepartment of Chemistry , Yale University , P.O. Box 208107, New Haven , Connecticut 06520-8107 , United States.
Elizabeth R JarvoDepartment of Chemistry , Yale University , P.O. Box 208107, New Haven , Connecticut 06520-8107 , United States.ORCID 0000-0002-2818-4038
Brandon Q MercadoDepartment of Chemistry , Yale University , P.O. Box 208107, New Haven , Connecticut 06520-8107 , United States.
Scott J MillerDepartment of Chemistry , Yale University , P.O. Box 208107, New Haven , Connecticut 06520-8107 , United States.ORCID 0000-0001-7817-1318
Yale University · US

Funding

Selective Peptide-Based Oxidation Catalysts for Bioactive Molecule SynthesisR01GM096403 · NIGMS · YALE UNIVERSITY · PI MILLER, SCOTT J · 2011 to 2018
$2.4M
NIGMS NIH HHS R01 GM096403
6 · The paper itself

Abstract

We herein report two examples of one-pot, simultaneous reactions, mediated by multiple, orthogonal catalysts with the same catalytic motif. First, BINOL-derived chiral phosphoric acids (CPA) and phosphothreonine (pThr)-embedded peptides were found to be matched for two different steps in double reductions of bisquinolines. Next, two π-methylhistidine (Pmh)-containing peptides catalyzed enantio- and chemoselective acylations and phosphorylations of multiple substrates in one pot. The selectivity exhibited by common reactive moieties is adjusted solely by the appended chiral scaffold through outer-sphere interactions.

Indexed as

CatalysisMolecular StructureNaphtholsPeptidesPhosphoric AcidsPhosphothreonineBINOL, naphtholNaphtholsPeptidesPhosphoric AcidsPhosphothreonine

Identifiers

PMID30608173
PMCPMC6358474
OpenAlexW2908117486

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.