Evidence map›Paper›PMID 30608049›Full record

Observational studyThe American journal of tropical medicine and hygiene2019

Etanercept to Control Inflammation in the Treatment of Complicated Neurocysticercosis.

Theodore E Nash, JeanAnne M Ware, Christina M Coyle, Siddhartha Mahanty

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in The American journal of tropical medicine and hygiene, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Calcified Neurocysticercosis: Understanding Dead (Not Necessarily Inactive) Parasites.The American journal of tropical medicine and hygiene · 2025
    Review
  5. Article
  6. Article
  7. Human Neurocysticercosis: An Overview.Pathogens (Basel, Switzerland) · 2022
    Review
  8. Review
  9. Frequency and Determinant Factors for Calcification in Neurocysticercosis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  10. Review
  11. Review
  12. Subarachnoid neurocysticercosis: emerging concepts and treatment.Current opinion in infectious diseases · 2020
    Review
  13. Unique Characteristics of Epilepsy Development in Neurocysticercosis.The American journal of tropical medicine and hygiene · 2020
    Review
  14. Review
  15. Natural History of Treated Subarachnoid Neurocysticercosis.The American journal of tropical medicine and hygiene · 2020
    Article
  16. Optimal Treatment for Subarachnoid Neurocysticercosis: Closer, but Not There yet.The American journal of tropical medicine and hygiene · 2020
    Article
  17. Article
  18. Controlling the Host Response in Neurocysticercosis.The American journal of tropical medicine and hygiene · 2019
    Article
  19. Therapeutic advances in neuroinfectious diseases.Therapeutic advances in infectious disease
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Theodore E NashLaboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.
JeanAnne M WareLaboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.
Christina M CoyleDepartment of Medicine, Albert Einstein College of Medicine, Bronx, New York.
Siddhartha MahantyLaboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.
National Institute of Allergy and Infectious Diseases · USAlbert Einstein College of Medicine · US

Funding

Clinical And Therapeutic Studies Of Human Filariasis and Related DiseasesZIAAI000439 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI NUTMAN, THOMAS · 2009 to 2025
$14.8M
Studies of neurocysticercosis and animal cestode infectionsZIAAI000846 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI NASH, THEODORE · 2009 to 2020
$9.5M
6 · The paper itself

Abstract

Manifestations of neurocysticercosis (NCC) are primarily due to host inflammatory responses directed at drug-damaged or naturally degenerating metacestodes (cysts) of the tapeworm

Indexed as

AdultAlbendazoleAnthelminticsAnti-Inflammatory Agents, Non-SteroidalEtanerceptFemaleHumansInflammationMaleMiddle AgedNeurocysticercosisPraziquantelYoung AdultAlbendazoleAnthelminticsAnti-Inflammatory Agents, Non-SteroidalEtanerceptPraziquantel

Identifiers

PMID30608049
PMCPMC6402894
OpenAlexW2906882082

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.