Evidence map›Paper›PMID 30608004›Full record

ArticleAntioxidants & redox signaling2019

Bioenergetic Differences in the Airway Epithelium of Lean

Daniel Winnica, Catherine Corey, Steven Mullett, Michael Reynolds, Gabrielle Hill, Stacy Wendell, Loretta Que, Fernando Holguin, Sruti Shiva

Open access · greenAbstract read
In one paragraph

Article in Antioxidants & redox signaling, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 76 citations in OpenAlex.

  1. Article
  2. Asthma endotypes and theratypes.Chinese medical journal pulmonary and critical care medicine · 2026
    Review
  3. Article
  4. Article
  5. Dysregulation of PKM2 promotes inflammatory response in allergic rhinitis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Article
  6. Review
  7. Asthma Phenotypes and Biomarkers.Respiratory care · 2025
    Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Multifaceted roles of mitochondria in asthma.Cell biology and toxicology · 2024
    Review
  14. Weight Loss Interventions for Adults With Obesity-Related Asthma.The journal of allergy and clinical immunology. In practice · 2024
    Article
  15. Mitochondrial Dysfunction and Metabolic Reprogramming in Obesity and Asthma.International journal of molecular sciences · 2024
    Review
  16. Review
  17. Article
  18. Review
  19. Mitoquinone mesylate attenuates pathological features of lean and obese allergic asthma in mice.American journal of physiology. Lung cellular and molecular physiology · 2023
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Daniel WinnicaDivision of Pulmonary Allergy and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Catherine CoreyVascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Steven MullettHealth Sciences Metabolomics and Lipidomics Core, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Michael ReynoldsVascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Gabrielle HillVascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Stacy WendellHealth Sciences Metabolomics and Lipidomics Core, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Loretta QueDepartment of Pulmonary and Critical Care Medicine, Duke University School of Medicine, Durham, North Carolina.
Fernando HolguinDivision of Pulmonary Allergy and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Sruti ShivaVascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
University of Pittsburgh · USDuke University · US

Funding

Heme-induced platelet mtROS drives TSP1 release to accelerate PH pathogenesisR01HL133003 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SHIVA, SRUTI · 2017 to 2020
$1.6M
Bringing Untargeted Metabolomics to PittS10OD023402 · OD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GELHAUS, STACY LYNN · 2018 to 2018
$594k
The Effects of Nitrate/Nitrite and Conjugated Linoleic Acid Supplementation on the Obese Asthmatic PathologyR21AI122071 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GELHAUS, STACY LYNN · 2016 to 2017
$426k
NHLBI NIH HHS R01 HL133003NIAID NIH HHS R21 AI122071NIH HHS S10 OD023402
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAsthmaBlood PlateletsCells, CulturedEpitheliumFemaleHumansLungMaleMiddle AgedNitric OxideNitric Oxide SynthaseNitric Oxide Synthase Type IIObesityOxidative StressSignal TransductionNitric OxideNitric Oxide SynthaseNitric Oxide Synthase Type IIasthmaglycolysismetabolismmitochondriaobesity

Identifiers

PMID30608004
PMCPMC6708272
OpenAlexW2907436604

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.