Evidence map›Paper›PMID 30607891›Full record

ArticleJournal of neurovirology2019

Post-transplant primary central nervous system lymphoma after Epstein-Barr virus cerebellitis.

Cristina Valencia-Sanchez, Kristen K Steenerson, Katalin Kelemen, Robert Orenstein, Shimon Kusne, Marie F Grill

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Journal of neurovirology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Cristina Valencia-SanchezDivision of Neurology, Mayo Clinic Arizona, 13400 East Shea Boulevard, Scottsdale, AZ, 85259, USA. valenciasanchez.cristina@mayo.edu.ORCID 0000-0003-0116-8035
Kristen K SteenersonOtology & Neurotology Division, Stanford Ear Institute, 2452 Watson Ct Ste 1500, Palo Alto, CA, 94303, USA.
Katalin KelemenDivision of Laboratory Medicine and Pathology, Mayo Clinic Arizona, 5777 East Mayo Boulevard, Phoenix, AZ, 85054, USA.
Robert OrensteinDivision of Infectious Diseases, Mayo Clinic Arizona, 5777 East Mayo Boulevard, Phoenix, AZ, 85054, USA.
Shimon KusneDivision of Infectious Diseases, Mayo Clinic Arizona, 5777 East Mayo Boulevard, Phoenix, AZ, 85054, USA.
Marie F GrillDivision of Neurology, Mayo Clinic Arizona, 13400 East Shea Boulevard, Scottsdale, AZ, 85259, USA.
WinnMed · USMayo Clinic in Arizona · USCalifornia Ear Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-transplantation lymphoproliferative disorder (PTLD) is a complication of solid organ and hematopoietic stem cell transplantation. Cases with isolated central nervous system (CNS) disease are rare. Epstein-Barr virus (EBV) plays a causative role. We present a patient with EBV cerebellitis documented 5 months prior to development of primary CNS PTLD (PCNS-PTLD). This case report demonstrates progression from EBV CNS infection to lymphoproliferative disorder, highlighting the importance of serial clinical and imaging monitoring in transplant patients post-EBV CNS infection. PCNS-PTLD should always be considered in the differential diagnosis for transplant patients presenting with CNS symptoms, even in cases with no evidence of EBV viremia. Earlier diagnosis and appropriate treatment could result in improved outcomes.

Indexed as

Kidney TransplantationAntineoplastic AgentsCentral Nervous SystemCentral Nervous System DiseasesEpstein-Barr Virus InfectionsFatal OutcomeFemaleHerpesvirus 4, HumanHumansImmunosuppressive AgentsLymphomaMagnetic Resonance ImagingMiddle AgedRecurrenceAntineoplastic AgentsImmunosuppressive AgentsEpstein-Barr virus encephalitisNeurological complications solid organ transplantPost-transplant lymphoproliferative disorderPrimary central nervous system lymphoma

Identifiers

PMID30607891
OpenAlexW2908372143

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.