ArticleInternational ophthalmology2019
Retinal vascular density evaluated by optical coherence tomography angiography in macular telangiectasia type 2.
Article in International ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 17 citations in OpenAlex.
- Morphological, vascular, and functional changes in macular telangiectasia type 2 in Egyptian patients.Scientific reports · 2025Article
- Skeleton density and ellipsoid zone loss are prognostic for progression in Macular Telangiectasia Type 2.Scientific reports · 2024Article
- Evaluation of Optic Disc, Retinal Vascular Structures, and Acircularity Index in Patients with Idiopathic Macular Telangiectasia Type 2.Diagnostics (Basel, Switzerland) · 2023Article
- Use of OCT Angiography to Diagnose and Manage Atypical Presentations of Macular Telangiectasia Type 2.International journal of molecular sciences · 2022Article
- Optical Coherence Tomography Angiography in Healthy Adult Subjects: Normative Values, Frequency, and Impact of Artifacts.BioMed research international · 2022Article
- Does size of telangiectasia on optical coherence tomography angiography influence vision in eyes with type 2 macular telangiectasia?Indian journal of ophthalmology · 2021Article
- Assessing the Influence of OCT-A Device and Scan Size on Retinal Vascular Metrics.Translational vision science & technology · 2020Article
- Perivenular Capillary Loss: An Early, Quantifiable Change in Macular Telangiectasia Type 2.Translational vision science & technology · 2020Article
- Overlap between telangiectasia and photoreceptor loss increases with progression of macular telangiectasia type 2.PloS one · 2019Article
- Evaluation of 1-year follow-up results of macular telangiectasia type 2 cases by optical coherence tomography angiography.GMS ophthalmology cases · 2019Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate the retinal and choroidal vascular changes through optical coherence tomography angiography (OCTA) in patients with macular telangiectasia type 2 (MacTel 2).
methodsOur study included 20 patients (40 eyes) with MacTel 2, and age-matched and sex-matched 18 subjects (36 eyes) in the control group. Fundus color photographs, fundus autofluorescence, fundus fluorescein angiography, spectral-domain optical coherence tomography and OCTA were performed. Foveal vascular density and parafoveal vascular density (PFVD), and foveal retinal thickness and parafoveal retinal thickness, choroidal thickness (CT) and retinal ganglion cell-inner plexiform layer (GCIPL) were compared between MacTel 2 patients and normal age-matched controls.
resultsThe retinal whole vascular density and PFVD of the deep plexus were significantly lower in patients with MacTel 2 than that of the control group (56.93% vs. 58.54%, p = 0.003; and 60.38% vs. 61.66%, p = 0.045). The foveal avascular zone (FAZ) of the deep plexus was significantly enlarged in patients with MacTel 2 than that of the control group (0.44 vs. 0.36, p = 0.009). There was a positive and statistically significant correlation between the FAZ of the superficial and deep plexus and CT in patients with MacTel 2. There was a positive and statistically significant correlation between retinal whole, parafoveal temporal quadrant vascular density of the superficial and deep plexus and GCIPL thickness in patients with MacTel 2.
conclusionsOur study demonstrated that important retinal vascular density and FAZ changes in MacTel 2 occur in the deep capillary plexus of the retina.
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