Trial reportAIDS and behavior2019
Randomized Control Trial of Culturally Adapted Cognitive Processing Therapy for PTSD Substance Misuse and HIV Sexual Risk Behavior for Native American Women.
Trial report in AIDS and behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05070793 (Improving Alcohol Use Disorder Treatment for Gender Minority Populations), which is not on this map. Cited by 29 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Improving Alcohol Use Disorder Treatment for Gender Minority Populations
Who cites it
29 citing papers in PubMed, 7 syntheses or guidelines pooled it, 60 citations in OpenAlex.
- Cultural Adaptations to the Assessment and Treatment of Trauma Experiences Among Racial and Ethnic Minority Groups: A Mixed-Methods Systematic Review and Meta-Analysis.Trauma, violence & abuse · 2026Pooled it
- Cognitive-behavioral interventions for co-occurring substance use and mental health disorders.Drug and alcohol dependence · 2025Pooled it
- Project harmony: A systematic review and network meta-analysis of psychotherapy and pharmacologic trials for comorbid posttraumatic stress, alcohol, and other drug use disorders.Psychological bulletin · 2024Pooled it
- A Systematic Review of Trauma and Substance Use in American Indian and Alaska Native Individuals: Incorporating Cultural Considerations.Journal of racial and ethnic health disparities · 2023Pooled it
- Systematic review of Indigenous involvement and content in mental health interventions and their effectiveness for Indigenous populations.The Australian and New Zealand journal of psychiatry · 2022Pooled it
- Culturally adapted evidence-based treatments for adults with substance use problems: A systematic review and meta-analysis.Drug and alcohol dependence · 2021Pooled it
- Pooled it
- Integrated PTSD and adherence treatment for people living with HIV: a feasibility pilot trial for cognitive processing therapy- lifesteps (CPT-L) at a Ryan white clinic.AIDS research and therapy · 2025Trial
- A pilot randomized controlled trial of cognitive restructuring for PTSD and alcohol misuse following recent sexual assault: Initial efficacy and feasibility.Behaviour research and therapy · 2025Trial
- A Randomized Comparison Trial Testing Two Culturally Adapted HIV Prevention Approaches for Native Americans Reducing Trauma Symptoms Versus Substance Misuse.AIDS and behavior · 2025Trial
- Trial
- Trial
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- Considerations for Spiritually Integrated Cognitive Processing Therapy (SICPT) for PTSD and Posttraumatic Growth in Survivors of Interpersonal Trauma.Journal of religion and health · 2026Article
- Contextual and culturally adapted interventions to improve HIV outcomes: a scoping review.BMC infectious diseases · 2025Article
- The predictive association between social support, communal mastery, and response to culturally adapted cognitive processing therapy among Native American women.Journal of traumatic stress · 2025Article
- Innovating through tradition: kava-Frontiers in psychology · 2025Review
- A scoping review of nursing interventions to reduce PTSD in adolescents who have been sexually abused.BMC nursing · 2024Article
- Posttraumatic stress disorder in people who use drugs: syringe services program utilization, treatment need, and preferences for onsite mental health care.Harm reduction journal · 2024Article
- A Community Engaged Approach in Adapting Motivational Interviewing and Skills Training for Native Americans With Experiences of Substance Misuse.American journal of health promotion : AJHP · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
An overlooked sequela of HIV risk is trauma exposure, yet few HIV interventions address trauma exposure, mental health, and substance misuse. In a two-arm randomized controlled trial 73 Native American women were randomized to a culturally-adapted Cognitive Processing Therapy (CPT) or 6-weeks waitlist. Outcomes assessed: PTSD symptom severity, alcohol use frequency, substance abuse or dependence diagnosis, and high-risk sexual behavior defined as vaginal/anal intercourse (a) under the influence of alcohol and/or illicit substances, (b) with a partner who was concurrently sexually active with someone else, and/or (c) with more than one partner in the past 6 weeks. Among immediate intervention participants, compared to waitlist participants, there were large reductions in PTSD symptom severity, high-risk sexual behavior, and a medium-to-large reduction in the frequency of alcohol use. CPT appears to improve mental health and risk behaviors, suggesting that addressing PTSD may be one way of improving HIV-risk related outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.