Evidence map›Paper›PMID 30607659›Full record

ArticlePsychometrika2019

Latent Class Dynamic Mediation Model with Application to Smoking Cessation Data.

Jing Huang, Ying Yuan, David Wetter

Abstract readEvaluation Study
In one paragraph

Article in Psychometrika, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jing HuangDepartment of Biostatistics, Epidemiology and Informatics, The University of Pennsylvania, Philadelphia, PA, USA.
Ying YuanDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. yyuan@mdanderson.org.
David WetterHuntsman Center for HOPE and the Department of Population Health Sciences, The University of Utah, Salt Lake City, UT, USA.

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
NCI NIH HHS P30 CA016672
6 · The paper itself

Abstract

Traditional mediation analysis assumes that a study population is homogeneous and the mediation effect is constant over time, which may not hold in some applications. Motivated by smoking cessation data, we propose a latent class dynamic mediation model that explicitly accounts for the fact that the study population may consist of different subgroups and the mediation effect may vary over time. We use a proportional odds model to accommodate the subject heterogeneities and identify latent subgroups. Conditional on the subgroups, we employ a Bayesian hierarchical nonparametric time-varying coefficient model to capture the time-varying mediation process, while allowing each subgroup to have its individual dynamic mediation process. A simulation study shows that the proposed method has good performance in estimating the mediation effect. We illustrate the proposed methodology by applying it to analyze smoking cessation data.

Indexed as

Data Interpretation, StatisticalLatent Class AnalysisSmoking CessationAdolescentAdultAgedBayes TheoremComputer SimulationFemaleHumansMiddle AgedRandomized Controlled Trials as TopicStatistics, NonparametricYoung AdultBayesian inferencedynamic mediationlatent classtime-varying coefficients

Identifiers

PMID30607659
PMCPMC6594758

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.