Evidence map›Paper›PMID 30607617›Full record

ArticleJournal of bone and mineral metabolism2019

Metabolic characteristics of subjects with spine-femur bone mineral density discordances: the Korean National Health and Nutrition Examination Survey (KNHANES 2008-2011).

A Ram Hong, Jung Hee Kim, Ji Hyun Lee, Sang Wan Kim, Chan Soo Shin

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Article in Journal of bone and mineral metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

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16citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Quantitative computed tomography provides improved accuracy for diagnosis of lumbar osteoporosis in patients with facet joint osteoarthritis: a cross-sectional study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
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  14. Increasing fasting glucose and fasting insulin associated with elevated bone mineral density-evidence from cross-sectional and MR studies.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021
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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

A Ram HongDepartment of Internal Medicine, Chonnam National University Medical School, Gwangju, South Korea.
Jung Hee KimDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea.
Ji Hyun LeeDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea.
Sang Wan KimDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea.
Chan Soo ShinDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea. csshin@snu.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The diagnosis of osteoporosis is determined based on the lowest bone mineral density (BMD) T-score at the lumbar spine (LS) and hip. However, there are occasional marked discordances between the T-score of LS and femur neck (FN). We aimed to examine the prevalence and characteristics of individuals with spine-femur BMD discordance using a nationwide survey. A total of 3233 men aged ≥ 50 years and 2915 postmenopausal women were included from the Korean National Health and Nutrition Examination Surveys (2008-2011). The spine-femur discordance was defined as a difference of ≥ 1.5 SD between LS and FN BMD. Subjects were divided into three groups: low LS (LS < FN), low FN (LS > FN), and no discordance. Four-hundred and seventeen men (12.9%) and two hundred and ninety women (10%) exhibited spine-femur BMD discordance. The prevalence of hypertension and diabetes was higher in men and women with low FN BMD than in any other group. Fasting plasma glucose and homeostasis model assessment of insulin resistance was the highest in subjects with low FN BMD among the three groups. Low FN BMD revealed higher serum parathyroid hormone and lower 25-hydroxyvitamin D3 levels compared to any other group in women, but this was not observed in men. Osteoporosis was prevalent in subjects with discordance in both genders, particularly, in those with low LS BMD (31.6% in men and 63.5% in women). Given the high prevalence of spine-femur BMD discordance, low FN BMD may be associated with vitamin D deficiency and insulin resistance, but low LS BMD may present severe osteoporosis.

Indexed as

Bone DensityNutrition SurveysAgedFemaleFemurHumansMaleMiddle AgedOsteoporosisPrevalenceRepublic of KoreaSpineBone mineral densityOsteoporosisSpine–femur discordanceT-score

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.