ArticleLangenbeck's archives of surgery2019
Stringent fluid management might help to prevent postoperative ileus after loop ileostomy closure.
Article in Langenbeck's archives of surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07144969 (Comparison of the Effect of Chewing Gum and Honey on Postoperative Recovery and Complications in Ileostomy Reversal), which is not on this map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparison of the Effect of Chewing Gum and Honey on Postoperative Recovery and Complications in Ileostomy Reversal
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Association between vedolizumab and postoperative complications in IBD: a systematic review and meta-analysis.International journal of colorectal disease · 2021Pooled it
- Robotic versus laparoscopic rectal resection: impact on primary postoperative ileus and the role of intraoperative fluid balance: a propensity score-matched cohort study.Surgical endoscopy · 2026Article
- Intraoperative Fluid Balance and Perioperative Complications in Ovarian Cancer Surgery.Annals of surgical oncology · 2024Article
- Assessing the perioperative gain of weight (Δweight) as a determinant of morbidity after kidney transplantation: a retrospective exploratory study.Scientific reports · 2024Article
- Perioperative Fluid Management in Colorectal Surgery: Institutional Approach to Standardized Practice.Journal of clinical medicine · 2024Review
- Proof-of-concept for intervention to prevent post-operative ileus in patients undergoing ileostomy formation.Perioperative medicine (London, England) · 2022Article
- Postoperative paralytic ileus following debulking surgery in ovarian cancer patients.Frontiers in surgery · 2022Article
- Self-administered succus entericus reinfusion before ileostomy closure improves short-term outcomes.BMC surgery · 2021Article
- Risk factors and outcomes associated with postoperative ileus following ileostomy formation: a retrospective study.Perioperative medicine (London, England) · 2021Article
- Effect of intraoperative fluid volume on postoperative ileus after robot-assisted radical cystectomy.Scientific reports · 2021Article
- Risk factors for postoperative ileus following loop ileostomy closure.Turkish journal of surgery · 2020Article
- Correlation of postoperative fluid balance and weight and their impact on outcomes.Langenbeck's archives of surgery · 2020Article
- Perioperative fluids and complications after pancreatoduodenectomy within an enhanced recovery pathway.Scientific reports · 2020Article
- Goal-Directed vs Traditional Approach to Intraoperative Fluid Therapy during Open Major Bowel Surgery: Is There a Difference?Anesthesiology research and practice · 2019Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe present study aimed to analyze the impact of perioperative fluid management on postoperative ileus (POI) after loop ileostomy closure.
methodsConsecutive loop ileostomy closures over a 6-year period (May 2011-May 2017) were included. Main outcomes were POI, defined as time to first stool beyond POD 3, and postoperative complications of any grade. Critical fluid management-related thresholds including postoperative weight gain were identified through receiver operator characteristics (ROC) analysis and tested in a multivariable analysis.
resultsOf 238 included patients, 33 (14%) presented with POI; overall complications occurred in 91 patients (38%). 1.7 L IV fluids at postoperative day (POD) 0 was determined a critical threshold for POI (area under ROC curve (AUROC), 0.64), yielding a negative predictive value (NPV) of 93%. Further, a critical cutoff for a postoperative weight gain of 1.2 kg at POD 2 was identified (AUROC, 0.65; NPV, 95%). Multivariable analysis confirmed POD 0 fluids of > 1.7 L (OR, 4.7; 95% CI, 1.4-15.3; p = 0.01) and POD 2 weight gain of > 1.2 kg (OR, 3.1; 95% CI, 1-9.4; p = 0.046) as independent predictors for POI.
conclusionsPerioperative fluid administration of > 1.7 L and POD 2 weight gain of > 1.2 kg represent critical thresholds for POI after loop ileostomy closure.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.