Evidence map›Paper›PMID 30607444›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2019

Effect of (Z)-isomer content on [

Kelly Smart, Sylvia M L Cox, Alexey Kostikov, Aliaksandr Shalai, Stephanie G Scala, Maria Tippler, Natalia Jaworska, Michel Boivin, Jean R Séguin, Chawki Benkelfat and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. A Review of Molecular Imaging of Glutamate Receptors.Molecules (Basel, Switzerland) · 2020
    Review
  3. mGlu5 receptor availability in youth at risk for addictions: effects of vulnerability traits and cannabis use.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2020
    Article
  4. Sex differences in [European journal of nuclear medicine and molecular imaging · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kelly SmartDepartment of Psychiatry, McGill University, 1033 Pine Avenue West, Montreal, QC, H3A 1A1, Canada. kelly.smart@mail.mcgill.ca.ORCID http://orcid.org/0000-0002-4775-6943
Sylvia M L CoxDepartment of Psychiatry, McGill University, 1033 Pine Avenue West, Montreal, QC, H3A 1A1, Canada.
Alexey KostikovDepartment of Neurology & Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, QC, H3A 2B4, Canada.
Aliaksandr ShalaiDepartment of Psychiatry, McGill University, 1033 Pine Avenue West, Montreal, QC, H3A 1A1, Canada.
Stephanie G ScalaDepartment of Psychiatry, McGill University, 1033 Pine Avenue West, Montreal, QC, H3A 1A1, Canada.
Maria TipplerDepartment of Psychiatry, McGill University, 1033 Pine Avenue West, Montreal, QC, H3A 1A1, Canada.
Natalia JaworskaDepartment of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, K1H 8M5, Canada.
Michel BoivinDepartment of Psychology, Université Laval, Laval, QC, G1V 0A6, Canada.
Jean R SéguinCHU Ste-Justine Research Center, Montreal, QC, H3T 1C5, Canada.
Chawki BenkelfatDepartment of Psychiatry, McGill University, 1033 Pine Avenue West, Montreal, QC, H3A 1A1, Canada.
Marco LeytonDepartment of Psychiatry, McGill University, 1033 Pine Avenue West, Montreal, QC, H3A 1A1, Canada.

Funding

Canadian Institutes of Health Research 97910Canadian Institutes of Health Research MOP119509Canadian Institutes of Health Research MOP133537Fonds de Recherche du Québec - Santé (CA) 981055 and 991027Fonds de recherche du Quebec - Société et culture 2002-RS-79238 and 2009-RG-124779Social Sciences and Humanities Research Council of Canada 839-2000-1008 and 410-99-1048
6 · The paper itself

Abstract

purposeTo determine how the low-affinity (Z)-isomer of the radiotracer [

methodsHigh-resolution [

resultsMean ± SD (E)-isomer content in [

conclusionsEven modest levels of (Z)-[

Indexed as

Carbon RadioisotopesFemaleHumansMaleOximesPositron-Emission TomographyProtein BindingPyridinesReceptor, Metabotropic Glutamate 5StereoisomerismYoung Adult3-(6-methylpyridin-2-ylethynyl)cyclohex-2-enone-O-methyloximeCarbon-11Carbon RadioisotopesOximesPyridinesReceptor, Metabotropic Glutamate 5[11C]ABP688Metabotropic glutamate receptorsmGluR5PETPositron emission tomography

Identifiers

PMID30607444

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.