Evidence map›Paper›PMID 30607371›Full record

ArticleWellcome open research2018

Metabolic tracing reveals novel adaptations to skeletal muscle cell energy production pathways in response to NAD

Lucy A Oakey, Rachel S Fletcher, Yasir S Elhassan, David M Cartwright, Craig L Doig, Antje Garten, Alpesh Thakker, Oliver D K Maddocks, Tong Zhang, Daniel A Tennant and 2 more

Open access · goldAbstract read
In one paragraph

Article in Wellcome open research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Trigonelline is an NADNature metabolism · 2024
    Article
  3. NADNature cell biology · 2023
    Article
  4. Article
  5. Cardiomyocyte-Specific Wt1 Is Involved in Cardiac Metabolism and Response to Damage.Journal of cardiovascular development and disease · 2023
    Article
  6. Article
  7. Review
  8. NADSports medicine (Auckland, N.Z.) · 2022
    Review
  9. Review
  10. Nuclear NADeLife · 2021
    Article
  11. Article
  12. NADCell reports · 2021
    Article
  13. Complementary NADSkeletal muscle · 2020
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Lucy A OakeyInstitute of Metabolism and Systems Research, University of Birmingham, UK, Birmingham, B15 2TT, UK.ORCID https://orcid.org/0000-0001-7664-5428
Rachel S FletcherInstitute of Metabolism and Systems Research, University of Birmingham, UK, Birmingham, B15 2TT, UK.
Yasir S ElhassanInstitute of Metabolism and Systems Research, University of Birmingham, UK, Birmingham, B15 2TT, UK.ORCID https://orcid.org/0000-0002-2735-6053
David M CartwrightInstitute of Metabolism and Systems Research, University of Birmingham, UK, Birmingham, B15 2TT, UK.
Craig L DoigInstitute of Metabolism and Systems Research, University of Birmingham, UK, Birmingham, B15 2TT, UK.
Antje GartenInstitute of Metabolism and Systems Research, University of Birmingham, UK, Birmingham, B15 2TT, UK.ORCID https://orcid.org/0000-0002-5354-287X
Alpesh ThakkerInstitute of Metabolism and Systems Research, University of Birmingham, UK, Birmingham, B15 2TT, UK.ORCID https://orcid.org/0000-0003-3901-0479
Oliver D K MaddocksInstitute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK.ORCID https://orcid.org/0000-0002-5551-9091
Tong ZhangInstitute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK.
Daniel A TennantInstitute of Metabolism and Systems Research, University of Birmingham, UK, Birmingham, B15 2TT, UK.ORCID https://orcid.org/0000-0003-0499-2732
Christian LudwigInstitute of Metabolism and Systems Research, University of Birmingham, UK, Birmingham, B15 2TT, UK.ORCID https://orcid.org/0000-0001-8901-6970
Gareth G LaveryInstitute of Metabolism and Systems Research, University of Birmingham, UK, Birmingham, B15 2TT, UK.
University of Pennsylvania · USUniversity of Glasgow · GB

Funding

Cancer Research UK 19702Wellcome Trust
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

aspartateisotopic tracingmetabolismNAD+NAMPTNRskeletal muscle

Identifiers

PMID30607371
PMCPMC6305244
OpenAlexW2901212753

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.