ArticleBMC hematology2018
The role of haematological indices in predicting early iron deficiency among pregnant women in an urban area of Sri Lanka.
Article in BMC hematology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Role of iron in the reduction of anemia among women of reproductive age in low-middle income countries: insights from systematic review and meta-analysis.BMC women's health · 2023Pooled it
- Clinical utility of calculated haematological parameters in the diagnosis of iron deficiency anaemia in pregnant women.Biomedical reports · 2025Article
- Anaemia in First Trimester: Proportion, Selected Causes and Associated Factors among First Trimester Pregnant Women Attending Antenatal Clinics in Colombo District, Sri Lanka.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2025Article
- Diagnostic Accuracy of Hemoglobin Levels and Red Blood Cell Parameters for Iron Deficiency in Adolescents: A Cross-Sectional Study.Global pediatric health · 2024Article
- Using complete blood count parameters in the diagnosis of iron deficiency and iron deficiency anemia in Filipino women.Journal of rural medicine : JRM · 2023Article
- Is Restless Legs Syndrome De Facto Thyroid Disease?Biomedicines · 2022Article
- Prevalence and aetiologies of anaemia among first trimester pregnant women in Sri Lanka; the need for revisiting the current control strategies.BMC pregnancy and childbirth · 2022Article
- Anemia in Ugandan pregnant women: a cross-sectional, systematic review and meta-analysis study.Tropical medicine and health · 2021Article
- Baseline iron and low-grade inflammation modulate the effectiveness of iron supplementation: evidence from follow-up of pregnant Sri Lankan women.European journal of nutrition · 2021Article
- Utility of erythrocyte indices in identifying iron depletion in pregnancy.Obstetric medicine · 2021Article
- Cross-sectional study to assess etiology and associated factors for anaemia during first trimester of pregnancy in Anuradhapura District, Sri Lanka: a protocol.F1000Research · 2021Article
- Maternal Anaemia in Pregnancy: A Significantly Greater Risk Factor for Anaemia in Australian Aboriginal Children than Low Birth Weight or Prematurity.Maternal and child health journal · 2020Article
- Role of Reticulocyte Parameters in Anemia of First Trimester Pregnancy: A Single Center Observational Study.Journal of laboratory physicians · 2020Article
- A possible role for hepcidin in the detection of iron deficiency in severely anaemic HIV-infected patients in Malawi.PloS one · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEarly detection and treatment of iron deficiency during pregnancy is crucial for optimum pregnancy outcomes. Anaemia is a late indictor of iron deficiency measured as Hb < 11 g/dL, and is widely used as a proxy for iron deficiency. We aimed to evaluate the role of red cell indices as a screening tool for early detection of iron deficiency among pregnant women in an urban area of Sri Lanka.
methodA cross-sectional study was conducted among 110 apparently healthy pregnant women ≤12 weeks of gestation attending antenatal clinics in Colombo, Sri Lanka. Women already on nutritional supplements were excluded. Full blood count, serum ferritin (SF) and high sensitive C-reactive protein (hs-CRP) assessments were performed. The women with evidence of inflammation as indicated by hs-CRP > 10 mg/L were excluded (
resultsOf the 90 women, 63 (70.0%) were iron deficient (SF < 30 μg/L), out of whom 10 (15.9%) were identified as having iron deficiency anaemia (Hb < 11 g/dL). A high sensitivity (> 70%) in the prediction of iron deficiency was obtained for the optimal cut-off values of Hb < 12.2 g/dL, MCV < 83.2 fl, MCH < 26.9 pg and MCHC 33.2 g/dL while maintaining a specificity > 40%.
conclusionIron deficiency can be predicted in early stages using Hb and red cell indices, which is much less expensive. This could be a useful method in areas with limited resources and a high prevalence of iron deficiency.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.