Evidence map›Paper›PMID 30606714›Full record

ArticleThe EMBO journal2019

CDK phosphorylation of

Bradley T French, Aaron F Straight

Open access · bronzeAbstract read
In one paragraph

Article in The EMBO journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 32 citations in OpenAlex.

  1. Structure and function of the centromere and inner kinetochore.Nature reviews. Molecular cell biology · 2026
    Review
  2. Article
  3. Dual Roads of CENP-A for Centromere Identification.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. The CENP-A chaperone complex spatially organizes centromeres.bioRxiv : the preprint server for biology · 2025
    Article
  9. Article
  10. Preserving centromere identity: right amounts of CENP-A at the right place and time.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2025
    Review
  11. A brief historical perspective on cell cycle control of CENP-A assembly and inheritance.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2025
    Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Centromere Identity and the Regulation of Chromosome Segregation.Frontiers in cell and developmental biology · 2022
    Review
  17. Article
  18. Article
  19. The N-terminal tail ofMolecular biology of the cell · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Bradley T FrenchDepartment of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA.ORCID 0000-0001-7397-7814
Aaron F StraightDepartment of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA astraigh@stanford.edu.ORCID 0000-0001-5885-7881
Stanford University · US

Funding

Supplement to Enhance Wellness and Resiliency in the Graduate EnvironmentT32GM007276 · NIGMS · STANFORD UNIVERSITY · PI MORRISON, ASHBY J. · 1985 to 2023
$32.9M
Mechanisms of Kinetochore AssemblyR01GM074728 · NIGMS · STANFORD UNIVERSITY · PI Aaron F Straight · 2005 to 2026
$6.6M
NIGMS NIH HHS R01 GM074728NIGMS NIH HHS T32 GM007276
6 · The paper itself

Abstract

Chromosome segregation requires the centromere, the site on chromosomes where kinetochores assemble in mitosis to attach chromosomes to the mitotic spindle. Centromere identity is defined epigenetically by the presence of nucleosomes containing the histone H3 variant CENP-A. New CENP-A nucleosome assembly occurs at the centromere every cell cycle during G1, but how CENP-A nucleosome assembly is spatially and temporally restricted remains poorly understood. Centromere recruitment of factors required for CENP-A assembly is mediated in part by the three-protein Mis18 complex (Mis18α, Mis18β, M18BP1). Here, we show that

Indexed as

Chromatin Assembly and DisassemblyMetaphaseAmino Acid SequenceAnimalsCarrier ProteinsCell DivisionCentromereCentromere Protein AChromosomal Proteins, Non-HistoneChromosome SegregationCyclin-Dependent KinasesNucleosomesPhosphorylationProtein BindingSequence HomologyXenopus laevisCarrier ProteinsCentromere Protein Acentromere protein CChromosomal Proteins, Non-HistoneCyclin-Dependent KinasesM18BP1 protein, XenopusNucleosomesXenopus ProteinsCENP‐ACENP‐Ccentromereepigenetics

Identifiers

PMID30606714
PMCPMC6376277
OpenAlexW2949171315

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.