Evidence map›Paper›PMID 30606266›Full record

ReviewSubstance abuse treatment, prevention, and policy2019

HIV prevention intervention for substance users: a review of the literature.

Adel Elkbuli, Valerie Polcz, Brianna Dowd, Mark McKenney, Guillermo Prado

Open access · goldAbstract readReview
In one paragraph

Review in Substance abuse treatment, prevention, and policy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 47 citations in OpenAlex.

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  20. Methamphetamine and Cannabis: A Tale of Two Drugs and their Effects on HIV, Brain, and Behavior.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Adel ElkbuliDepartment of Public Health Sciences, University of Miami Miller School of Medicine, Miami, Florida, USA. adel.elkbuli@hcahealthcare.com.ORCID http://orcid.org/0000-0001-7730-617X
Valerie PolczDepartment of Surgery, Kendall Regional Medical Center, Miami, Florida, USA.
Brianna DowdDepartment of Surgery, Kendall Regional Medical Center, Miami, Florida, USA.
Mark McKenneyDepartment of Surgery, Kendall Regional Medical Center, Miami, Florida, USA.
Guillermo PradoDepartment of Public Health Sciences, University of Miami Miller School of Medicine, Miami, Florida, USA.
Florida International University · USUniversity of Miami · USUniversity of South Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBehavioral Interventions are needed to prevent HIV in substance users, which is associated with higher risk for contracting HIV via unprotected sexual intercourse or syringe-based exposure. We reviewed universal HIV prevention interventions targeting intravenous drug users (IDUs) and non-IDUs (NIDUs) to identify which prevention interventions are the most effective at reducing HIV transmission risk among IDU's and NIDU's and identify gaps in the literature.

methodsA PubMed literature review (1998-2017), limiting studies to universal HIV prevention interventions targeting adult HIV-negative substance users. Interventions were compared across sample sizes, sociodemographic, intervention setting, study design, use of theoretical models, and intervention effects.

resultsOf 1455 studies identified, 19 targeted IDUs (n = 9) and NIDUs (n = 10). Both IDU and NIDU studies were conducted in substance use treatment centers and included both group (44% vs. 73%) and individual-based (56% vs. 27%) methods; only one NIDU study used a couple-based intervention. All IDU, and 89% of NIDU, studies used explanatory and behavior-change theoretical models to guide selection of intervention mechanisms. Reduction in frequency of risky sexual behaviors were observed in 33% IDU and 64% NIDU studies, where 56% of IDU studies effectively increased drug use-related hygiene and 67% decreased frequency of injections. Eight studies included start-of-study HIV testing and five examined HIV seroconversion.

conclusionThe interventions reviewed demonstrate promising results for decreasing risky sexual practices for NIDUs and reducing high-risk drug practices for IDUs, thereby reducing HIV transmission risk. Future studies should include HIV testing and measurement of HIV seroconversion to fully elucidate intervention effects.

Indexed as

Risk Reduction BehaviorDrug UsersHIV InfectionsHumansSubstance Abuse, IntravenousUnsafe SexBehavioral interventionsDrug use disorderHIV/AIDSInjection drug usersIntervention effectivenessSexual behaviorUniversal HIV prevention interventions

Identifiers

PMID30606266
PMCPMC6318880
OpenAlexW2908295709

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.