ArticleBMC pediatrics2019
Puberty timing associated with obesity and central obesity in Chinese Han girls.
Article in BMC pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04251559 (Evaluation of the Relationship Between Age at Menarche and Gestational Diabetes Mellitus), which is not on this map. Cited by 39 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of the Relationship Between Age at Menarche and Gestational Diabetes Mellitus
Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 124 citations in OpenAlex.
- Worldwide Secular Trends in Age at Pubertal Onset Assessed by Breast Development Among Girls: A Systematic Review and Meta-analysis.JAMA pediatrics · 2020Pooled it
- Weight status is associated with puberty timing in girls in Isfahan province, Iran.BMJ paediatrics open · 2026Article
- The complex interaction between obesity and puberty and its implications for pubertal timing: a review of recent evidence.Endocrine connections · 2026Review
- Basal Luteinizing Hormone Combined with Age and BMI as a Simplified Screening Model for Central Precocious Puberty in Girls.International journal of women's health · 2026Article
- The influence of adiposity status and the trajectories of obesity indicators on earlier puberty onset in girls: a longitudinal cohort study in Shanghai, China.BMC public health · 2025Article
- Trajectories and predictors of spherical equivalent among multiethnic school-aged children in Southwest China: a 2.5-year cohort study.BMJ open · 2025Article
- Diagnostic Value of Single LH and LH/FSH Ratio at 60-minute after GnRHa Stimulation Test for Central Precocious Puberty.Indian journal of pediatrics · 2025Article
- The Interplay Between Body Weight and the Onset of Puberty.Children (Basel, Switzerland) · 2025Review
- Identification of loci associated with women's reproductive traits and exploration of a shared genetic basis with obesity.Human genomics · 2025Article
- Research on Body Composition and Lifestyle Behaviors During Pubertal Development in 6-12-Year-Old Children with Obesity.Healthcare (Basel, Switzerland) · 2025Article
- Clinical and epidemiological insights into early puberty in Thai girls: a 5-year study.Annals of pediatric endocrinology & metabolism · 2025Article
- The role of body composition and appetite-regulating hormones in idiopathic central precocious puberty and their changes during GnRH analog therapy.Journal of endocrinological investigation · 2025Article
- Association of Age at Menarche with General and Abdominal Obesity in Young Women.Medicina (Kaunas, Lithuania) · 2024Article
- Central Precocious Puberty During the COVID-19 Pandemic Period: A Systematic Review of Literature.Cureus · 2024Review
- Trends of socioeconomic and geographic inequalities in severe wasting among under-five children in Ethiopia from 2000 to 2019: using the WHO Health Equity Assessment Toolkit.Scientific reports · 2024Article
- Determinants of HIV infection at 18 months of age among HIV-exposed infants in the context of PMTCT interventions in southern Ethiopia.Frontiers in reproductive health · 2024Article
- Relationship between Body Mass Index and Bone Turnover Markers in Girls with Idiopathic Central Precocious Puberty.International journal of clinical practice · 2023Article
- The influence of the trajectory of obesity indicators on the age of pubertal onset and pubertal tempo in girls: A longitudinal study in Chongqing, China.Frontiers in public health · 2023Article
- Precocious puberty under stressful conditions: new understanding and insights from the lessons learnt from international adoptions and the COVID-19 pandemic.Frontiers in endocrinology · 2023Review
- Leptin, ghrelin, nesfatin-1, and orexin-A plasma levels in girls with premature thelarche.Journal of endocrinological investigation · 2022Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is growing scientific evidence supports a link between increased childhood adiposity and early onset of puberty in girls worldwide in recent decades. However, the data from Chinese girls remain ambiguous. The aims of this study were to estimate the puberty milestones and examine attainment of puberty associated with obesity and central obesity in Chinese Han schoolgirls.
methodsThe cross-sectional school-based study examined 2996 Han schoolgirls aged 9 to 19 years from 6 provinces in China. Trained clinicians assessed the girls for height, weight, waist circumference, Tanner stages of breast and pubic hair development, and menarcheal status. We classified girls as normal weight, overweight, or obese based on BMI, and as normal weight or central obese based on the waist-height ratio, then estimated and compared median age at a given Tanner stage or greater by weight class using Probit models.
resultsThe median age at menarche was 12.36 years. The median ages at breast stages(B) 2 through 5 were 10.03, 11.38, 13.39, and 15.79 years, respectively, and at pubic hair stages(PH) 2 through 5 were 11.62, 12.70, 14.38, and 16.92 years, respectively. Girls from urban areas experienced menarche, B3 and B4 stages, and PH3 through PH5 stages earlier. Girls with central obesity and overweight/obesity reached puberty earlier at almost every Tanner stage of breast and pubic hair than normal girls. Girls with obesity developed PH2 and PH3 earlier than their overweight peers. However, we did not find any significant differences between girls with overweight and obesity at all stages of breast development.
conclusionsChildhood obesity, including both overweight/obesity and central obesity, is associated with earlier attainment of puberty in Chinese Han schoolgirls.
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