Evidence map›Paper›PMID 30606123›Full record

ArticleBMC infectious diseases2019

Is a positive Christie-Atkinson-Munch-Peterson (CAMP) test sensitive enough for the identification of Streptococcus agalactiae?

Dacheng Guo, Yu Xi, Shanmei Wang, Zeyu Wang

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. CAMP-negative group B Streptococcus in pregnant women: molecular and clinical features with implications for diagnostics and neonatal management.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  3. Article
  4. Article
  5. Characterization of Virulence Factors and Antimicrobial Susceptibility ofAnimals : an open access journal from MDPI · 2024
    Article
  6. Article
  7. Article
  8. Multicenter Evaluation of the Cepheid Xpert GBS LB XC Test.Journal of clinical microbiology · 2022
    Article
  9. Article
  10. Virulence Factor Genes and Cytotoxicity ofMicrobiology spectrum · 2022
    Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Dacheng GuoInstitute for Infectious Disease Control and Prevention, Henan Provincial Center for Disease Control and Prevention, Zhengzhou, China.
Yu XiSchool of Life Sciences, Zhengzhou University, Zhengzhou, China.
Shanmei WangDepartment of Clinical Laboratory, Henan Provincial People's Hospital, Zhengzhou, China.
Zeyu WangR&D Center, Autobio Diagnostics Co. Ltd, Zhengzhou, China. pine8844@126.com.ORCID http://orcid.org/0000-0002-5112-9555
Henan Provincial Center for Disease Control and Prevention · CNHenan Provincial People's Hospital · CNMBio Diagnostics (United States) · USZhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFor a long time, the Christie-Atkinson-Munch-Peterson (CAMP) test has been a standard test for the identification of Streptococcus agalactiae, and a positive result for S.agalactiae has been considered sensitive enough.

methodsTo confirm whether a positive CAMP test is a requirement for the identification of S.agalactiae, five suspected CAMP-negative S.agalactiae isolates from two hospitals, confirmed as Gram-positive and catalase-negative streptococci, were verified by the CAMP test in three batches of plates from two manufacturers and identified by the Phoenix system, MALDI-TOF MS, the PCR assay and the 16S rDNA gene sequencing.

resultsAll five suspected strains were S.agalactiae, four of which were CAMP-negative and one of which was not S.agalactiae by the PCR assay.

conclusionsA positive CAMP test was lacking sensitivity for the identification of S.agalactiae, and the question of whether the cfb gene is worthy of targeting should be further studied.

Indexed as

Bacteriological TechniquesDNA, RibosomalFemaleHumansPolymerase Chain ReactionSensitivity and SpecificitySpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationStreptococcal InfectionsStreptococcus agalactiaeVaginaDNA, Ribosomal16S rDNA gene sequencingCAMP testPCRStreptococcus agalactiae

Identifiers

PMID30606123
PMCPMC6318942
OpenAlexW2947415729

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.