ArticleCell reports2019
High-Affinity Bent β
Open access · goldAbstract read
In one paragraph
Article in Cell reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 55 citations in OpenAlex.
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- Nanoscopy reveals integrin clustering reliant on kindlin-3 but not talin-1.Cell communication and signaling : CCS · 2025Article
- The Integrin Receptors: From Discovery to Structure to Medicines.Immunological reviews · 2025Review
- Ezrin drives adaptation of monocytes to the inflamed lung microenvironment.Cell death & disease · 2024Article
- Review
- A Flow Cytometry-Based High-Throughput Technique for Screening Integrin-Inhibitory Drugs.Journal of visualized experiments : JoVE · 2024Article
- LFA-1 nanoclusters integrate TCR stimulation strength to tune T-cell cytotoxic activity.Nature communications · 2024Article
- Cryo-EM structures of full-length integrin αIIbβ3 in native lipids.Nature communications · 2023Article
- Clustering of phosphatase RPTPα promotes Src signaling and the arthritogenic action of synovial fibroblasts.Science signaling · 2023Article
- Advances in NK cell therapy for brain tumors.NPJ precision oncology · 2023Review
- Targeting integrin pathways: mechanisms and advances in therapy.Signal transduction and targeted therapy · 2023Review
- INTEGRINS: A BEDSIDE TO BENCH TO BEDSIDE STORY.Transactions of the American Clinical and Climatological Association · 2023Article
- Single-Molecule Imaging of Membrane Proteins on Vascular Endothelial Cells.Journal of lipid and atherosclerosis · 2023Review
- Nexinhib20 Inhibits Neutrophil Adhesion and βJournal of immunology (Baltimore, Md. : 1950) · 2022Article
- Heterotropic roles of divalent cations in the establishment of allostery and affinity maturation of integrin αXβ2.Cell reports · 2022Article
- Integrin Regulators in Neutrophils.Cells · 2022Review
- Review
- Immune Cell Plasticity in Inflammation: Insights into Description and Regulation of Immune Cell Phenotypes.Cells · 2022Review
- A humanized βCell reports · 2022Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 3 institutions in 3 countries.
Zhichao FanDivision of Inflammation Biology, La Jolla Institute for Immunology, 9420 Athena Circle Drive, La Jolla, CA 92037, USA.
William Bill KiossesMicroscopy Core Facility, La Jolla Institute for Immunology, 9420 Athena Circle Drive, La Jolla, CA 92037, USA.
Hao SunDepartment of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
Marco OrecchioniDivision of Inflammation Biology, La Jolla Institute for Immunology, 9420 Athena Circle Drive, La Jolla, CA 92037, USA.
Yanal GhoshehDivision of Inflammation Biology, La Jolla Institute for Immunology, 9420 Athena Circle Drive, La Jolla, CA 92037, USA.
Dirk M ZajoncDivision of Immune Regulation, La Jolla Institute for Immunology, 9420 Athena Circle Drive, La Jolla, CA 92037, USA; Department of Internal Medicine, Faculty of Medicine and Health Sciences, Ghent University, 9000 Ghent, Belgium.
M Amin ArnaoutHarvard Medical School, Boston, MA 02115, USA; Leukocyte Biology and Inflammation Program, Massachusetts General Hospital, Boston, MA 02114, USA; Division of Nephrology, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA; Center for Regenerative Medicine, Medical Services, Massachusetts General Hospital, Boston, MA 02114, USA.
Edgar GutierrezDepartment of Physics, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
Alex GroismanDepartment of Physics, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
Mark H GinsbergDepartment of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
Klaus LeyDivision of Inflammation Biology, La Jolla Institute for Immunology, 9420 Athena Circle Drive, La Jolla, CA 92037, USA; Department of Bioengineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA. Electronic address: klaus@lji.org.
La Jolla Institute for Immunology · USUniversity of California San Diego · USHarvard University · US
Funding
The Interaction of TPO and Integrins in Hematopoiesis CellsP01HL078784 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GINSBERG, MARK HOWARD · 2005 to 2019
$28.3MStructure and Function of beta2 IntegrinR01DK048549 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI ARNAOUT, M. AMIN · 1994 to 2016
$6.0MDeconvoluting the Vascular AdhesomeR35HL139947 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GINSBERG, MARK HOWARD · 2018 to 2024
$5.5MStructure and Function of Integrins in the KidneyR01DK088327 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI ARNAOUT, M. AMIN · 2010 to 2025
$5.3MSuper-resolution confocal microscopeS10OD021831 · OD · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI LEY, KLAUS F. · 2017 to 2017
$566kAmerican Heart Association-American Stroke Association 16POST31160014American Heart Association-American Stroke Association 18CDA34110426NHLBI NIH HHS P01 HL078784NHLBI NIH HHS R35 HL139947NIDDK NIH HHS R01 DK048549NIDDK NIH HHS R01 DK088327NIH HHS S10 OD021831
Abstract
Leukocyte adhesion requires β
Indexed as
CD18 AntigensCell Adhesion MoleculesHumansNeutrophilsProtein BindingCD18 AntigensCell Adhesion Moleculeshumanintegrinintegrin activationmolecular modelingneutrophilSTORMsuperresolutionTIRF
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.