ArticleExperimental eye research2019
Lack of cone mediated retinal function increases susceptibility to form-deprivation myopia in mice.
Abstract read
In one paragraph
Article in Experimental eye research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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0cells of the map it votes in
27citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 33 citations in OpenAlex.
- Prevention of myopia in a near-primate by supplemental indigo light suggests a hypothesis for the myopia boom.Cell reports. Medicine · 2026Article
- The IGF2-ERK-Fos axis drives a Müller cell glial-mesenchymal transition-like response to disrupt retinal homeostasis in early myopia.Cell communication and signaling : CCS · 2026Article
- Dual-Hit Myopia Mechanism Unveiled by Multi-Omics: Opn1mw Deficiency Primed the Retina for Exaggerated Response to Environmental Defocus.Investigative ophthalmology & visual science · 2026Article
- Visualizing Extracellular Dopamine Dynamics in the Retina Reveals a Biphasic Reduction During Initial Myopia Development.Investigative ophthalmology & visual science · 2026Article
- Cellular Biological Basis and Novel Breakthroughs in the Pathogenesis of Myopia - A Narrative Review.International journal of general medicine · 2026Review
- Bidirectional Phosphorylation Changes in Opsins Associated With Early Myopia and Hyperopia Signal Regulation by Phosphoproteomics.Investigative ophthalmology & visual science · 2025Article
- Loss of ON-Pathway Function in Mice Lacking Lrit3 Decreases Recovery From Lens-Induced Myopia.Investigative ophthalmology & visual science · 2024Article
- Insights into Myopia from Mouse Models.Annual review of vision science · 2024Review
- Empagliflozin repurposing in Parkinson's disease; modulation of oxidative stress, neuroinflammation, AMPK/SIRT-1/PGC-1α, and wnt/β-catenin pathways.Inflammopharmacology · 2024Article
- The role of vasoactive intestinal peptide (VIP) in atropine-related inhibition of the progression of myopia.BMC ophthalmology · 2024Article
- Update on central factors in myopia development beyond intraocular mechanisms.Frontiers in neurology · 2024Review
- The Role of Retinal Dopamine D1 Receptors in Ocular Growth and Myopia Development in Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- The Role of Retinal Dysfunction in Myopia Development.Cellular and molecular neurobiology · 2023Review
- Cellular and Molecular Mechanisms of Pathogenesis Underlying Inherited Retinal Dystrophies.Biomolecules · 2023Review
- Encephalopsin (OPN3) is required for normal refractive development and the GO/GROW response to induced myopia.Molecular vision · 2023Article
- Mice LackingInternational journal of molecular sciences · 2022Article
- Altered Retinal Dopamine Levels in a Melatonin-proficient Mouse Model of Form-deprivation Myopia.Neuroscience bulletin · 2022Article
- Eyes on CHARGE syndrome: Roles of CHD7 in ocular development.Frontiers in cell and developmental biology · 2022Review
- The Role of Retinal Connexins Cx36 and Horizontal Cell Coupling in Emmetropization in Guinea Pigs.Investigative ophthalmology & visual science · 2021Article
- IMI 2021 Yearly Digest.Investigative ophthalmology & visual science · 2021Review
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Ranjay ChakrabortyDepartment of Ophthalmology, Emory University School of Medicine, 1365B Clifton Rd NE, Atlanta, GA, 30322, USA; Center for Visual and Neurocognitive Rehabilitation, Atlanta VA Healthcare System, 1670 Clairmont Rd, Decatur, GA, 30033, USA; College of Nursing and Health Sciences, Flinders University, Bedford Park, SA, 5001, Adelaide, Australia.
Victoria YangCenter for Visual and Neurocognitive Rehabilitation, Atlanta VA Healthcare System, 1670 Clairmont Rd, Decatur, GA, 30033, USA.
Han Na ParkDepartment of Ophthalmology, Emory University School of Medicine, 1365B Clifton Rd NE, Atlanta, GA, 30322, USA; Center for Visual and Neurocognitive Rehabilitation, Atlanta VA Healthcare System, 1670 Clairmont Rd, Decatur, GA, 30033, USA.
Erica G LandisDepartment of Ophthalmology, Emory University School of Medicine, 1365B Clifton Rd NE, Atlanta, GA, 30322, USA; Center for Visual and Neurocognitive Rehabilitation, Atlanta VA Healthcare System, 1670 Clairmont Rd, Decatur, GA, 30033, USA.
Susov DhakalDepartment of Ophthalmology, Emory University School of Medicine, 1365B Clifton Rd NE, Atlanta, GA, 30322, USA.
Cara T MotzCenter for Visual and Neurocognitive Rehabilitation, Atlanta VA Healthcare System, 1670 Clairmont Rd, Decatur, GA, 30033, USA.
Michael A BergenDepartment of Ophthalmology, Emory University School of Medicine, 1365B Clifton Rd NE, Atlanta, GA, 30322, USA; Center for Visual and Neurocognitive Rehabilitation, Atlanta VA Healthcare System, 1670 Clairmont Rd, Decatur, GA, 30033, USA.
P Michael IuvoneDepartment of Ophthalmology, Emory University School of Medicine, 1365B Clifton Rd NE, Atlanta, GA, 30322, USA; Department of Pharmacology, Emory University School of Medicine, 1365B Clifton Rd NE, Atlanta, GA, 30322, USA.
Machelle T PardueCenter for Visual and Neurocognitive Rehabilitation, Atlanta VA Healthcare System, 1670 Clairmont Rd, Decatur, GA, 30033, USA; Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, 313 Ferst Dr, Atlanta, GA, 30332, USA. Electronic address: machelle.pardue@bme.gatech.edu.
Atlanta VA Health Care System · USEmory University · USFlinders University · AU
Funding
P30-Core Grant for Vision Research Core CP30EY006360 · NEI · EMORY UNIVERSITY · PI GEISERT, ELDON E · 1986 to 2025
$15.3MNeuromodulators and Circadian Clocks: Roles in Retinal Function and DysfunctionR01EY004864 · NEI · EMORY UNIVERSITY · PI IUVONE, P MICHAEL · 1985 to 2018
$7.0MRetinal Mechanisms of Refractive DevelopmentR01EY016435 · NEI · GEORGIA INSTITUTE OF TECHNOLOGY · PI Machelle T. Pardue · 2009 to 2026
$5.4MVIsion Science Training in AtlantaT32EY007092 · NEI · EMORY UNIVERSITY · PI Machelle T. Pardue · 1985 to 2026
$4.6MRegulation of eye development by an Opsin5-dopamine pathwayR01EY027711 · NEI · EMORY UNIVERSITY · PI IUVONE, P MICHAEL, LANG, RICHARD A. · 2017 to 2020
$1.9MLight regulated vascular development in the eye via the Hippo pathwayR01EY032029 · NEI · CINCINNATI CHILDRENS HOSP MED CTR · PI LANG, RICHARD A., XIN, MEI · 2021 to 2024
$1.6MRR&D Research Career Scientist Award ApplicationIK6RX003134 · VA · VETERANS HEALTH ADMINISTRATION · PI PARDUE, MACHELLE T. · 2019 to 2025
–NEI NIH HHS P30 EY006360NEI NIH HHS R01 EY004864NEI NIH HHS R01 EY016435NEI NIH HHS R01 EY027711NEI NIH HHS R01 EY032029NEI NIH HHS T32 EY007092RRD VA IK6 RX003134
Abstract
Retinal photoreceptors are important in visual signaling for normal eye growth in animals. We used Gnat2
Indexed as
3,4-Dihydroxyphenylacetic AcidAnimalsChromatography, High Pressure LiquidDisease Models, AnimalDisease SusceptibilityDopamineFemaleHeterotrimeric GTP-Binding ProteinsMaleMiceMice, Inbred C57BLMyopiaRefraction, OcularRetinaRetinal Cone Photoreceptor CellsSensory Deprivation3,4-Dihydroxyphenylacetic AcidDopamineGnat2 protein, mouseHeterotrimeric GTP-Binding ProteinsCone photoreceptorsDopamineForm-deprivationGnat2MouseRefractive error
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.