Evidence map›Paper›PMID 30605656›Full record

ArticleNeuron2019

Sodium Is Detected by the OVLT to Regulate Sympathetic Tone.

Patrice G Guyenet

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuron, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Small-Conductance CaNeuroscience bulletin · 2026
    Review
  2. Structure and Function of the Blood-Brain Barrier (BBB).Handbook of experimental pharmacology · 2022
    Article
  3. Central respiratory chemoreception.Handbook of clinical neurology · 2022
    Review
  4. Review
4 · The record

Corrections and comments

  • Comment on
    [Na2019
5 · Who and what money

Authors and funding

1 author.

Patrice G GuyenetDepartment of Pharmacology, University of Virginia, Charlottesville, VA 22908, USA. Electronic address: pgg@virginia.edu.

Funding

Retrotrapezoid nucleus and central chemoreceptionR01HL074011 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI GUYENET, PATRICE G. · 2003 to 2018
$6.6M
Organization of Central Sympathic PathwaysR01HL028785 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI STORNETTA, RUTH L · 1985 to 2020
$5.0M
ORGANIZATION OF CENTRAL SYMPATHETIC PATHWAYSR37HL028785 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI GUYENET, PATRICE G. · 1999 to 2008
$3.0M
Ultrasound for Non-Invasive Prevention of Acute Kidney InjuryR01DK105133 · NIDDK · UNIVERSITY OF VIRGINIA · PI OKUSA, MARK DOUGLAS · 2015 to 2019
$2.4M
NHLBI NIH HHS R01 HL028785NHLBI NIH HHS R01 HL074011NHLBI NIH HHS R37 HL028785NIDDK NIH HHS R01 DK105133
6 · The paper itself

Abstract

Hypernatremia is known to elicit a rise in sympathetic tone and blood pressure. In this issue of Neuron, Nomura et al. (2018) now show that this is mediated via the organum vasculosum laminae terminalis (OVLT). Na

Indexed as

Body FluidsOrganum VasculosumAstrocytesBlood PressureSodiumSodium

Identifiers

PMID30605656
PMCPMC6738342

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.