Evidence map›Paper›PMID 30605563›Full record

ArticleAngewandte Chemie (International ed. in English)2019

Copper-Mediated Aminoquinoline-Directed Radiofluorination of Aromatic C-H Bonds with K

So Jeong Lee, Katarina J Makaravage, Allen F Brooks, Peter J H Scott, Melanie S Sanford

Open access · greenAbstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. C-H Labeling with [ACS central science · 2024
    Review
  7. Article
  8. Article
  9. Zinc-Mediated Radiosynthesis of Unprotected Fluorine-18 Labelled α-Tertiary Amides.Angewandte Chemie (International ed. in English) · 2024
    Article
  10. Article
  11. Preparation ofPharmaceutics · 2023
    Article
  12. Article
  13. Next Generation Copper Mediators for the Efficient Production ofChemistry (Weinheim an der Bergstrasse, Germany) · 2023
    Article
  14. Review
  15. Sequential Ir/Cu-Mediated Method for theJournal of the American Chemical Society · 2021
    Article
  16. Review
  17. Article
  18. Synthesis of high-molar-activity [Nature protocols · 2020
    Article
  19. NHC-Copper Mediated Ligand-Directed Radiofluorination of Aryl Halides.Journal of the American Chemical Society · 2020
    Article
  20. Synthesis of [Synthesis · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

So Jeong LeeDepartment of Radiology, University of Michigan, 1301 Catherine St, Ann Arbor, MI, 48109, USA.ORCID 0000-0003-0349-0765
Katarina J MakaravageDepartment of Chemistry, The University of Michigan, 930 North University Ave, Ann Arbor, MI, 48109, USA.ORCID 0000-0002-1225-5305
Allen F BrooksDepartment of Radiology, University of Michigan, 1301 Catherine St, Ann Arbor, MI, 48109, USA.ORCID 0000-0003-3773-3024
Peter J H ScottDepartment of Radiology, University of Michigan, 1301 Catherine St, Ann Arbor, MI, 48109, USA.ORCID 0000-0002-6505-0450
Melanie S SanfordDepartment of Chemistry, The University of Michigan, 930 North University Ave, Ann Arbor, MI, 48109, USA.ORCID 0000-0001-9342-9436
St. Catherine University · USUniversity of Michigan · US

Funding

Synthesis of Novel PET Radiotracers for Imaging in Alzheimer’s Disease and Related DisordersR01EB021155 · NIBIB · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SANFORD, MELANIE S., SCOTT, PETER JAMES HENRY · 2016 to 2024
$3.2M
NIBIB NIH HHS R01 EB021155NIH HHS R01EB021155U.S. Department of Energy DE-SC0012484
6 · The paper itself

Abstract

A Cu-mediated ortho-C-H radiofluorination of aromatic carboxylic acids that are protected as 8-aminoquinoline benzamides is described. The method uses K

Indexed as

AminoquinolinesBenzamidesBenzoatesCopperFluorine RadioisotopesHalogenationHumansRadiopharmaceuticalsReceptors, Retinoic AcidThiazoles4-(4-(2-(n-butoxy)ethoxy)-5-methylthiazol-2-yl)-2-fluorobenzoic acid8-aminoquinolineAminoquinolinesBenzamidesBenzoatesCopperFluorine-18Fluorine RadioisotopesRadiopharmaceuticalsReceptors, Retinoic Acidretinoic acid receptor betaThiazolesC−H fluorinationC−H functionalizationfluorine-18late-stage fluorinationPET radiochemistry

Identifiers

PMID30605563
PMCPMC6476334
OpenAlexW2907326005

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.