Evidence map›Paper›PMID 30605348›Full record

ArticleAmerican journal of respiratory cell and molecular biology2019

Myocardin Is Involved in Mesothelial-Mesenchymal Transition of Human Pleural Mesothelial Cells.

Torry Tucker, Yoshikazu Tsukasaki, Tsuyoshi Sakai, Shinya Mitsuhashi, Satoshi Komatsu, Ann Jeffers, Steven Idell, Mitsuo Ikebe

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory cell and molecular biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Myocardin regulates fibronectin expression and secretion from human pleural mesothelial cells.American journal of physiology. Lung cellular and molecular physiology · 2024
    Article
  5. Role of ZIP kinase in development of myofibroblast differentiation from HPMCs.American journal of physiology. Lung cellular and molecular physiology · 2024
    Article
  6. Review
  7. Article
  8. Calponin 1 contributes to myofibroblast differentiation of human pleural mesothelial cells.American journal of physiology. Lung cellular and molecular physiology · 2022
    Article
  9. DOCK2 Promotes Pleural Fibrosis by Modulating Mesothelial to Mesenchymal Transition.American journal of respiratory cell and molecular biology · 2022
    Article
  10. Update on Novel Targeted Therapy for Pleural Organization and Fibrosis.International journal of molecular sciences · 2022
    Review
  11. Article
  12. Article
  13. Endothelial Cell Protein C Receptor Deficiency AttenuatesAmerican journal of respiratory cell and molecular biology · 2021
    Article
  14. Article
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Torry TuckerDepartment of Cellular and Molecular Biology, University of Texas Health Science Center at Tyler, Tyler, Texas.
Yoshikazu TsukasakiDepartment of Cellular and Molecular Biology, University of Texas Health Science Center at Tyler, Tyler, Texas.
Tsuyoshi SakaiDepartment of Cellular and Molecular Biology, University of Texas Health Science Center at Tyler, Tyler, Texas.
Shinya MitsuhashiDepartment of Cellular and Molecular Biology, University of Texas Health Science Center at Tyler, Tyler, Texas.
Satoshi KomatsuDepartment of Cellular and Molecular Biology, University of Texas Health Science Center at Tyler, Tyler, Texas.
Ann JeffersDepartment of Cellular and Molecular Biology, University of Texas Health Science Center at Tyler, Tyler, Texas.
Steven IdellDepartment of Cellular and Molecular Biology, University of Texas Health Science Center at Tyler, Tyler, Texas.
Mitsuo IkebeDepartment of Cellular and Molecular Biology, University of Texas Health Science Center at Tyler, Tyler, Texas.
University of Illinois Urbana-Champaign · US

Funding

Myocardin in the pathogenesis of pleural remodelingR01HL142853 · NHLBI · UNIVERSITY OF TEXAS HLTH CTR AT TYLER · PI IDELL, STEVEN, IKEBE, MITSUO · 2019 to 2022
$1.9M
Fibrinolytic Proteases, meso-mesenchymal transition and pleural remodelingR01HL130133 · NHLBI · UNIVERSITY OF TEXAS HLTH CTR AT TYLER · PI TUCKER, TORRY ALLE · 2017 to 2021
$1.8M
Rac1 in Smooth MuscleR01HL111696 · NHLBI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI IKEBE, MITSUO · 2012 to 2016
$1.7M
The role of coagulation cascade proteases in pleural fibrosisK01HL115466 · NHLBI · UNIVERSITY OF TEXAS HLTH CTR AT TYLER · PI TUCKER, TORRY ALLE · 2012 to 2016
$551k
NHLBI NIH HHS K01 HL115466NHLBI NIH HHS R01 HL111696NHLBI NIH HHS R01 HL130133NHLBI NIH HHS R01 HL142853
6 · The paper itself

Abstract

Pleural fibrosis is characterized by severe inflammation of the pleural space and pleural reorganization. Subsequent thickening of the visceral pleura contributes to lung stiffness and impaired lung function. Pleural mesothelial cells (PMCs) can become myofibroblasts

Indexed as

Active Transport, Cell NucleusAdultAgedAged, 80 and overAnimalsBleomycinCell NucleusDisease Models, AnimalEmpyema, PleuralFemaleFibrosisHumansMaleMiceMiddle AgedMyocardinBleomycinMyocardinNuclear ProteinsSootTrans-ActivatorsTransforming Growth Factor betamesothelial–mesenchymal transitionmyocardinpleural fibrosissmooth muscleα-smooth muscle actin

Identifiers

PMID30605348
PMCPMC6604219
OpenAlexW2907318946

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.