Evidence map›Paper›PMID 30605311›Full record

ArticleACS applied materials & interfaces2019

Laser-Activatable CuS Nanodots to Treat Multidrug-Resistant Bacteria and Release Copper Ion to Accelerate Healing of Infected Chronic Nonhealing Wounds.

Yue Qiao, Yuan Ping, Hongbo Zhang, Bo Zhou, Fengyong Liu, Yinhui Yu, Tingting Xie, Wanli Li, Danni Zhong, Yuezhou Zhang and 3 more

Open access · hybridAbstract read
In one paragraph

Article in ACS applied materials & interfaces, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
18.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 218 citations in OpenAlex.

  1. Article
  2. Morphology-Dependent Antibacterial Activity of CuNanomaterials (Basel, Switzerland) · 2026
    Article
  3. Review
  4. Biofilm-Responsive Nanoplatforms for Infected Wound Reconstruction.International journal of nanomedicine · 2026
    Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Clays and Wound Healing.Materials (Basel, Switzerland) · 2024
    Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Yue QiaoEye Center & Department of Nuclear Medicine, The Second Affiliated Hospital , Zhejiang University School of Medicine , Hangzhou 310009 , China.
Yuan Ping
Hongbo ZhangDepartment of Pharmaceutical Science Laboratory , Åbo Akademi University , Turku 20520 , Finland.
Bo Zhou
Fengyong LiuDepartment of Interventional Radiology , Chinese PLA General Hospital , Beijing 100853 , China.
Yinhui YuEye Center & Department of Nuclear Medicine, The Second Affiliated Hospital , Zhejiang University School of Medicine , Hangzhou 310009 , China.
Tingting Xie
Wanli Li
Danni Zhong
Yuezhou ZhangDepartment of Pharmaceutical Science Laboratory , Åbo Akademi University , Turku 20520 , Finland.
Ke YaoEye Center & Department of Nuclear Medicine, The Second Affiliated Hospital , Zhejiang University School of Medicine , Hangzhou 310009 , China.
Min ZhouEye Center & Department of Nuclear Medicine, The Second Affiliated Hospital , Zhejiang University School of Medicine , Hangzhou 310009 , China.ORCID http://orcid.org/0000-0002-7319-9570
Zhejiang University · CNSecond Affiliated Hospital of Zhejiang University · CNÅbo Akademi University · FIChinese PLA General Hospital · CNUniversity of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic nonhealing wounds have imposed serious challenges in the clinical practice, especially for the patients infected with multidrug-resistant microbes. Herein, we developed an ultrasmall copper sulfide (covellite) nanodots (CuS NDs) based dual functional nanosystem to cure multidrug-resistant bacteria-infected chronic nonhealing wound. The nanosystem could eradicate multidrug-resistant bacteria and expedite wound healing simultaneously owing to the photothermal effect and remote control of copper-ion release. The antibacterial results indicated that the combination treatment of photothermal CuS NDs with photothermal effect initiated a strong antibacterial effect for drug-resistant pathogens including methicillin-resistant Staphylococcus aureus (MRSA) and extended-spectrum β-lactamase Escherichia coli both in vitro and in vivo. Meanwhile, the released Cu

Indexed as

AnimalsAnti-Bacterial AgentsCopperDrug Resistance, Multiple, BacterialHumansMethicillin-Resistant Staphylococcus aureusWound HealingAnti-Bacterial AgentsCoppercupric sulfideantibacterial effectchronic nonhealing woundcopper sulfide nanodotsmultidrug-resistant bacteriaphotothermal effects

Identifiers

PMID30605311
PMCPMC6727190
OpenAlexW2906764158

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.