Evidence map›Paper›PMID 30605223›Full record

ArticleJournal of applied toxicology : JAT2019

Single wall and multiwall carbon nanotubes induce different toxicological responses in rat alveolar macrophages.

Sara Nahle, Ramia Safar, Stéphanie Grandemange, Bernard Foliguet, Mélanie Lovera-Leroux, Zahra Doumandji, Alain Le Faou, Olivier Joubert, Bertrand Rihn, Luc Ferrari

Open access · hybridAbstract read
In one paragraph

Article in Journal of applied toxicology : JAT, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 39 citations in OpenAlex.

  1. Review
  2. Article
  3. Carbon Nanostructures for Ocular Tissue Reinforcement.Translational vision science & technology · 2022
    Article
  4. Review
  5. Review
  6. Article
  7. Evaluation ofIranian journal of biotechnology · 2021
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Sara NahleToxicology and Molecular Biology, Institute Jean Lamour UMR 7198 du CNRS, Université de Lorraine, F-54000, Nancy, France.ORCID 0000-0001-9853-709X
Ramia SafarToxicology and Molecular Biology, Institute Jean Lamour UMR 7198 du CNRS, Université de Lorraine, F-54000, Nancy, France.
Stéphanie GrandemangeToxicology and Molecular Biology, Institute Jean Lamour UMR 7198 du CNRS, Université de Lorraine, F-54000, Nancy, France.
Bernard FoliguetToxicology and Molecular Biology, Institute Jean Lamour UMR 7198 du CNRS, Université de Lorraine, F-54000, Nancy, France.
Mélanie Lovera-LerouxToxicology and Molecular Biology, Institute Jean Lamour UMR 7198 du CNRS, Université de Lorraine, F-54000, Nancy, France.
Zahra DoumandjiToxicology and Molecular Biology, Institute Jean Lamour UMR 7198 du CNRS, Université de Lorraine, F-54000, Nancy, France.
Alain Le FaouToxicology and Molecular Biology, Institute Jean Lamour UMR 7198 du CNRS, Université de Lorraine, F-54000, Nancy, France.
Olivier JoubertToxicology and Molecular Biology, Institute Jean Lamour UMR 7198 du CNRS, Université de Lorraine, F-54000, Nancy, France.
Bertrand RihnToxicology and Molecular Biology, Institute Jean Lamour UMR 7198 du CNRS, Université de Lorraine, F-54000, Nancy, France.
Luc FerrariToxicology and Molecular Biology, Institute Jean Lamour UMR 7198 du CNRS, Université de Lorraine, F-54000, Nancy, France.
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human exposure to airborne carbon nanotubes (CNT) is increasing because of their applications in different sectors; therefore, they constitute a biological hazard. Consequently, developing studies on CNT toxicity become a necessity. CNTs can have different properties in term of length, size and charge. Here, we compared the cellular effect of multiwall (MWCNTs) and single wall CNTs (SWCNTs). MWCNTs consist of multiple layers of graphene, while SWCNTs are monolayers. The effects of MWCNTs and SWCNTs were evaluated by the water-soluble tetrazolium salt cell proliferation assay on NR8383 cells, rat alveolar macrophage cell line (NR8383). After 24 hours of exposure, MWCNTs showed higher toxicity (50% inhibitory concentration [IC

Indexed as

Air PollutantsAnimalsCell LineMacrophages, AlveolarNanotubes, CarbonParticle SizeRatsSurface PropertiesAir PollutantsNanotubes, Carbonapoptosisinflammationin vitromultiwall carbon nanotubesMWCNToxidative stressrat macrophages cell line NR8383single wall carbon nanotubesSWCNT

Identifiers

PMID30605223
PMCPMC6590492
OpenAlexW2907184990

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.