Evidence map›Paper›PMID 30605131›Full record

ReviewActa crystallographica. Section D, Structural biology2018

The actions of volatile anesthetics: a new perspective.

Michael Weinrich, David L Worcester

Abstract readReview
In one paragraph

Review in Acta crystallographica. Section D, Structural biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Studies on the mechanism of general anesthesia.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Michael WeinrichNIST Center for Neutron Research, Gaithersburg, MD 20899, USA.
David L WorcesterNIST Center for Neutron Research, Gaithersburg, MD 20899, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article reviews recent work in applying neutron and X-ray scattering towards the elucidation of the molecular mechanisms of volatile anesthetics. Experimental results on domain mixing in ternary lipid mixtures, and the influence of volatile anesthetics and hydrostatic pressure are placed in the contexts of ion-channel function and receptor trafficking at the postsynaptic density.

Indexed as

AnestheticsAnimalsHumansHydrostatic PressureIon ChannelsMembrane LipidsMembrane MicrodomainsMembrane ProteinsNeuronal PlasticityNeutron DiffractionPost-Synaptic DensityReceptors, Cell SurfaceScattering, Small AngleVolatile Organic CompoundsX-Ray DiffractionAnestheticsIon ChannelsMembrane LipidsMembrane ProteinsReceptors, Cell SurfaceVolatile Organic Compoundsanesthesialipid raftsmembranesneutron scatteringsynaptic plasticity

Identifiers

PMID30605131
PMCPMC6317591

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.