Evidence map›Paper›PMID 30604756›Full record

ArticleNature communications2019

Ultrasensitive detection of miRNA with an antimonene-based surface plasmon resonance sensor.

Tianyu Xue, Weiyuan Liang, Yawen Li, Yuanhui Sun, Yuanjiang Xiang, Yupeng Zhang, Zhigao Dai, Yanhong Duo, Leiming Wu, Kun Qi and 5 more

Open access · goldAbstract readEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 131 papers.

0numbers the graph read from it
0cells of the map it votes in
131citing papers in PubMed
27.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

131 citing papers in PubMed, 735 citations in OpenAlex.

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71 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Tianyu XueKey Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Electronic Science and Technology and College of Optoelectronics Engineering, Shenzhen University, 518060, Shenzhen, People's Republic of China.
Weiyuan LiangKey Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Electronic Science and Technology and College of Optoelectronics Engineering, Shenzhen University, 518060, Shenzhen, People's Republic of China.
Yawen LiSchool of Materials Science and Engineering and Key Laboratory of Automobile Materials of MOE, Jilin University, 130012, Changchun, Jilin, People's Republic of China.
Yuanhui SunSchool of Materials Science and Engineering and Key Laboratory of Automobile Materials of MOE, Jilin University, 130012, Changchun, Jilin, People's Republic of China.
Yuanjiang XiangKey Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Electronic Science and Technology and College of Optoelectronics Engineering, Shenzhen University, 518060, Shenzhen, People's Republic of China.
Yupeng ZhangKey Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Electronic Science and Technology and College of Optoelectronics Engineering, Shenzhen University, 518060, Shenzhen, People's Republic of China.
Zhigao DaiDepartment of Materials Science and Engineering, ARC Centre of Excellence in Future Low-Energy Electronics Technologies (FLEET), Monash University, Clayton, VIC, 3800, Australia.
Yanhong DuoKey Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Electronic Science and Technology and College of Optoelectronics Engineering, Shenzhen University, 518060, Shenzhen, People's Republic of China.
Leiming WuKey Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Electronic Science and Technology and College of Optoelectronics Engineering, Shenzhen University, 518060, Shenzhen, People's Republic of China.
Kun QiKey Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Electronic Science and Technology and College of Optoelectronics Engineering, Shenzhen University, 518060, Shenzhen, People's Republic of China.
Bannur Nanjunda ShivananjuKey Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Electronic Science and Technology and College of Optoelectronics Engineering, Shenzhen University, 518060, Shenzhen, People's Republic of China.
Lijun ZhangSchool of Materials Science and Engineering and Key Laboratory of Automobile Materials of MOE, Jilin University, 130012, Changchun, Jilin, People's Republic of China. lijun_zhang@jlu.edu.cn.ORCID http://orcid.org/0000-0002-6438-5486
Xiaoqiang CuiSchool of Materials Science and Engineering and Key Laboratory of Automobile Materials of MOE, Jilin University, 130012, Changchun, Jilin, People's Republic of China. xqcui@jlu.edu.cn.
Han ZhangKey Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Electronic Science and Technology and College of Optoelectronics Engineering, Shenzhen University, 518060, Shenzhen, People's Republic of China. hzhang@szu.edu.cn.ORCID http://orcid.org/0000-0002-3185-5680
Qiaoliang BaoDepartment of Materials Science and Engineering, ARC Centre of Excellence in Future Low-Energy Electronics Technologies (FLEET), Monash University, Clayton, VIC, 3800, Australia. qiaoliang.bao@monash.edu.ORCID http://orcid.org/0000-0002-6971-789X
Shenzhen University · CNJilin University · CNARC Centre of Excellence in Future Low-Energy Electronics Technologies · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNA exhibits differential expression levels in cancer and can affect cellular transformation, carcinogenesis and metastasis. Although fluorescence techniques using dye molecule labels have been studied, label-free molecular-level quantification of miRNA is extremely challenging. We developed a surface plasmon resonance sensor based on two-dimensional nanomaterial of antimonene for the specific label-free detection of clinically relevant biomarkers such as miRNA-21 and miRNA-155. First-principles energetic calculations reveal that antimonene has substantially stronger interaction with ssDNA than the graphene that has been previously used in DNA molecule sensing, due to thanking for more delocalized 5s/5p orbitals in antimonene. The detection limit can reach 10 aM, which is 2.3-10,000 times higher than those of existing miRNA sensors. The combination of not-attempted-before exotic sensing material and SPR architecture represents an approach to unlocking the ultrasensitive detection of miRNA and DNA and provides a promising avenue for the early diagnosis, staging, and monitoring of cancer.

Indexed as

AntimonyBiomarkers, TumorBiosensing TechniquesDNA, Single-StrandedGraphiteHumansLab-On-A-Chip DevicesLimit of DetectionMicroRNAsNanostructuresNeoplasmsSensitivity and SpecificitySurface Plasmon ResonanceAntimonyBiomarkers, TumorDNA, Single-StrandedGraphiteMicroRNAs

Identifiers

PMID30604756
PMCPMC6318270
OpenAlexW2908340776

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.