Evidence map›Paper›PMID 30604398›Full record

ArticleBreast cancer (Tokyo, Japan)2019

Breast cancer incidence, mortality and mortality-to-incidence ratio (MIR) are associated with human development, 1990-2016: evidence from Global Burden of Disease Study 2016.

Rajesh Sharma

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Breast cancer (Tokyo, Japan), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05850637 (Phase II Study to Evaluate the Effectiveness and Toxicity of Adjuvant Ultra-hypofractionated Radiotherapy for the Treatment of Early and Locally Advanced Breast Cancer), which is not on this map. Cited by 98 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed, 9 pooled it
12.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05850637 phase2completednot on this map

Phase II Study to Evaluate the Effectiveness and Toxicity of Adjuvant Ultra-hypofractionated Radiotherapy for the Treatment of Early and Locally Advanced Breast Cancer

TypeinterventionalSponsorPrevent Senior InstituteRan2019 to 2023Enrolled60ConditionsBreast Cancer FemaleArmsadjuvant ultra-hypofractionated radiotherapy
3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 9 syntheses or guidelines pooled it, 236 citations in OpenAlex.

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  14. Assessment of transformer-based AI in clinical oncology.BMC medical informatics and decision making · 2025
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38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Rajesh SharmaUniversity School of Management and Entrepreneurship, Delhi Technological University, Vivek Vihar-Phase II, Delhi, 110095, India. rajesh.sharma@dtu.ac.in.
Delhi Technological University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine breast cancer burden in females using incidence, mortality and mortality-to-incidence ratio (MIR) and its association with human development.

methodsWe employ the data of breast cancer in females from the Global Burden of Disease 2016 study for the period 1990 to 2016 for 102 countries. Human development is measured using the human development index (HDI). 5-year survival rate of breast cancer is proxied using the mortality-to-incidence ratio (MIR).

findingsGlobally, breast cancer has claimed 535341 female lives and 1.7 million incident cases had surfaced in 2016. High incidence rates were observed in very high HDI countries led by the Netherlands (117.2/100,000), whereas the mortality rate was high in low/medium HDI countries led by Afghanistan (35.4/100,000). Breast cancer incidence has more than doubled in 60/102 countries, whereas deaths have doubled in 43/102 countries. Globally, breast cancer MIR decreased from 0.41 to 0.32 over 1990-2016 and displayed negative gradient with HDI (r = - 0.87), indicating a low 5-year survival in less developed countries.

conclusionHeterogeneity in breast cancer burden, as per human development, and increasing breast cancer incidence and low survival rates, indicated by MIR, call for broader human development, improving breast cancer awareness, and cost-effective screening and treatment in less developed countries.

Indexed as

Breast NeoplasmsFemaleGlobal Burden of DiseaseHumansIncidenceSocioeconomic FactorsSurvival RateBreast cancerIncidenceMortalityMortality-to-incidence ratio (MIR)

Identifiers

PMID30604398
OpenAlexW2908059055

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.