Evidence map›Paper›PMID 30604381›Full record

ArticleJournal of molecular neuroscience : MN2019

GM1 Acupoint Injection Improves Mental Retardation in Children with Cerebral Palsy.

Enyao Li, Pengju Zhao, Jie Jian, Hong Wu, Shuibo Gao, Hongyin Zhai

Abstract readControlled Clinical Trial
PubMed Publisher
In one paragraph

Article in Journal of molecular neuroscience : MN, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Enyao LiDepartment of Children Rehabilitation Medicine, Fifth Affiliated Hospital of Zhengzhou University, No. 3 rehabilitation Street, 27 District, Zhengzhou, 450052, Henan, China. 13526676676@126.com.ORCID http://orcid.org/0000-0002-9357-0875
Pengju ZhaoDepartment of Children Rehabilitation Medicine, Fifth Affiliated Hospital of Zhengzhou University, No. 3 rehabilitation Street, 27 District, Zhengzhou, 450052, Henan, China.
Jie JianDepartment of Children Rehabilitation Medicine, Fifth Affiliated Hospital of Zhengzhou University, No. 3 rehabilitation Street, 27 District, Zhengzhou, 450052, Henan, China.
Hong WuLaboratory, Henan Province Hospital of Traditional China Medicine, Zhengzhou, 450052, Henan, China.
Shuibo GaoLaboratory, Henan Province Hospital of Traditional China Medicine, Zhengzhou, 450052, Henan, China.
Hongyin ZhaiDepartment of Children Rehabilitation Medicine, Third Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China.
Fifth Affiliated Hospital of Zhengzhou University · CNThird Affiliated Hospital of Zhengzhou University · CNZhengzhou Children's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To study the clinical effectiveness and mechanism of GM1 acupoint injection therapy on mental retardation for children with cerebral palsy (CP). A total of 90 children with CP were divided into acupoint injection group (group A), subcutaneous injection group (group B), and control group (group C). Another 30 healthy children were set as a healthy control group (group D). The Mental Developmental Index (MDI), Psychomotor Developmental Index (PDI), and hemodynamic parameters in the cerebral arteries were measured before and after treatment. After three treatment courses, the MDI and PDI in groups A, B, and C were increased, and the increase in group A was most obvious (P < 0.05). Peak systolic velocity, mean velocity, and end-diastolic velocity were also elevated in group A, and after three treatment courses, resistance index decreased with a statistical significance (P < 0.05). However, there were no significant changes in groups B and C (P > 0.05). For all groups, neuron-specific enolase levels decreased and total superoxide dismutase increased after treatment. Acupoint injection therapy combined with conventional rehabilitation therapy demonstrated significant effects on cerebral hemodynamic conditions for children with CP.

Indexed as

Acupuncture PointsAcupuncture TherapyCerebral ArteriesCerebral PalsyChild, PreschoolFemaleG(M1) GangliosideHemodynamicsHumansInfantInjections, SubcutaneousIntellectual DisabilityMalePhosphopyruvate HydrataseSuperoxide DismutaseG(M1) GangliosidePhosphopyruvate HydrataseSuperoxide DismutaseAcupoint injectionCerebral blood flowCerebral palsyMental retardationRehabilitation therapy

Identifiers

PMID30604381
OpenAlexW2907845925

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.