Evidence map›Paper›PMID 30604346›Full record

ArticleLasers in medical science2019

Could a chelant improve the effect of curcumin-mediated photodynamic antimicrobial chemotherapy against dental intact biofilms?

Daniela Alejandra Cusicanqui Méndez, Veridiana Lopes Rizzato, Giuliana Campos Chaves Lamarque, Evandro José Dionisio, Marília Afonso Rabelo Buzalaf, Daniela Rios, Maria Aparecida Andrade Moreira Machado, Thiago Cruvinel

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Lasers in medical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. [Edta concentration in the effectiveness of antimicrobial photodynamic therapy with curcumin onRevista cientifica odontologica (Universidad Cientifica del Sur)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Daniela Alejandra Cusicanqui MéndezDepartment of Pediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry, University of São Paulo, Alameda Dr. Octavio Pinheiro Brisolla, 9-75, Vila Universitária, Bauru, São Paulo, 17012-901, Brazil.
Veridiana Lopes RizzatoDepartment of Pediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry, University of São Paulo, Alameda Dr. Octavio Pinheiro Brisolla, 9-75, Vila Universitária, Bauru, São Paulo, 17012-901, Brazil.
Giuliana Campos Chaves LamarqueDepartment of Pediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry, University of São Paulo, Alameda Dr. Octavio Pinheiro Brisolla, 9-75, Vila Universitária, Bauru, São Paulo, 17012-901, Brazil.
Evandro José DionisioDepartment of Pediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry, University of São Paulo, Alameda Dr. Octavio Pinheiro Brisolla, 9-75, Vila Universitária, Bauru, São Paulo, 17012-901, Brazil.
Marília Afonso Rabelo BuzalafDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru, Brazil.
Daniela RiosDepartment of Pediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry, University of São Paulo, Alameda Dr. Octavio Pinheiro Brisolla, 9-75, Vila Universitária, Bauru, São Paulo, 17012-901, Brazil.
Maria Aparecida Andrade Moreira MachadoDepartment of Pediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry, University of São Paulo, Alameda Dr. Octavio Pinheiro Brisolla, 9-75, Vila Universitária, Bauru, São Paulo, 17012-901, Brazil.
Thiago CruvinelDepartment of Pediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry, University of São Paulo, Alameda Dr. Octavio Pinheiro Brisolla, 9-75, Vila Universitária, Bauru, São Paulo, 17012-901, Brazil. thiagocruvinel@fob.usp.br.ORCID http://orcid.org/0000-0001-7095-908X
Universidade de São Paulo · BR

Funding

Funda??o de Amparo ? Pesquisa do Estado de S?o Paulo 2014/10890-0Funda??o de Amparo ? Pesquisa do Estado de S?o Paulo 2015/08595-9
6 · The paper itself

Abstract

To our knowledge, there is still no evidence in relation to the combination of curcumin with chelants to improve the effects of antimicrobial photodynamic therapy (aPDT) on complex dental caries biofilms. Therefore, the aim of this study was to evaluate the antimicrobial effect of curcumin-ethylenediaminetetraacetic acid (EDTA)-mediated aPDT on the vitality of intact biofilms of dentin caries microcosms. Biofilms were grown on glass slabs in McBain medium plus 1% sucrose in microaerophily at 37 °C for 5 days. Then, biofilms were treated with associations of 600 μmol L

Indexed as

PhotochemotherapyAnti-Bacterial AgentsAnti-Infective AgentsBiofilmsChelating AgentsChildCurcuminDental CariesHumansMicrobial ViabilityMicroscopy, ConfocalStreptococcus mutansAnti-Bacterial AgentsAnti-Infective AgentsChelating AgentsCurcuminBiofilmCurcuminDental cariesEthylenediaminetetraacetic acidPhotochemotherapy

Identifiers

PMID30604346
OpenAlexW2907227578

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.