SynthesisLasers in medical science2019
Enucleation of the prostate for benign prostatic hyperplasia thulium laser versus holmium laser: a systematic review and meta-analysis.
Synthesis in Lasers in medical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 4 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Endoscopic enucleation of the prostate versus transurethral resection of the prostate for benign prostatic hyperplasia: a systematic review and meta-analysis.Prostate cancer and prostatic diseases · 2025Pooled it
- Pulsed Thulium: YAG laser for the management of Urolothiasis: a systematic review from the EAU section of endourology.World journal of urology · 2025Pooled it
- The safety and efficacy of five surgical treatments in prostate enucleation: a network meta-analysis.BMC urology · 2024Pooled it
- Comparison of EEP and TURP long-term outcomes: systematic review and meta-analysis.World journal of urology · 2023Pooled it
- A prospective multicenter randomized comparison between Holmium Laser Enucleation of the Prostate (HoLEP) and Thulium Laser Enucleation of the Prostate (ThuLEP).World journal of urology · 2021Trial
- Pulsed Thulium:YAG laser enucleation versus open simple prostatectomy for large-gland benign prostatic hyperplasia: a retrospective comparative observational study.Translational andrology and urology · 2026Article
- Endoscopic enucleation of the prostate made practical: lessons from experts from the BEAM25 meeting.World journal of urology · 2026Review
- Evaluation of the Transition from Holmium:YAG to Pulsed Thulium:YAG for Laser Endoscopic Enucleation of the Prostate and the Effect on Procedural Performance.European urology open science · 2026Article
- Thulium YAG laser versus bipolar enucleation for management of benign prostate obstruction secondary to large prostates (>80 gm): A multicenter prospective randomized study.Arab journal of urology · 2026Article
- Three surgical techniques using different energy sources for anatomical endoscopic enucleation of the prostate.Frontiers in surgery · 2025Review
- Real-world experience with the new pulsed solid-state Thulium: YAG laser (Thulio) for endoscopic enucleation of the prostate.World journal of urology · 2024Article
- The thermal effect of lasers in urology: a review article.Lasers in medical science · 2023Review
- Thulium YAG is the Best Laser for the Prostate Because of Versatility.European urology open science · 2023Article
- Experimental ex-vivo performance study comparing a novel, pulsed thulium solid-state laser, chopped thulium fibre laser, low and high-power holmium:YAG laser for endoscopic enucleation of the prostate.World journal of urology · 2022Article
- Safety and Efficacy of Laser Enucleation of the Prostate in Elderly Patients - A Narrative Review.Clinical interventions in aging · 2022Review
- Current evidence of ThuLEP for BPH: A review of literature.Turkish journal of urology · 2021Article
- Reasons to go for thulium-based anatomical endoscopic enucleation of the prostate.World journal of urology · 2021Review
- Holmium laser enucleation of prostate by using en-bloc and bladder neck preservation technique: technical consideration and influence on functional outcomes.Translational andrology and urology · 2021Article
- [Surgical treatment of benign prostatic obstruction (BPO) in patients under anticoagulation: a review of the bleeding risks of established techniques].Der Urologe. Ausg. A · 2020Review
- Lasers in Transurethral Enucleation of the Prostate-Do We Really Need Them.Journal of clinical medicine · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
To evaluate the clinical efficacy and safety of thulium laser vapoenucleation/enucleation of the prostate (ThuEP) versus holmium laser enucleation of the prostate (HoLEP) in the management of benign prostatic hyperplasia (BPH). A systematic literature search was performed using PubMed, Embase, and Web of Science to identify eligible studies published before July 2018. Meta-analysis of extracted data was performed with RevMan version 5.3. We chose the fixed- or random-effect model to fit the pooled heterogeneity. Five eligible studies including two randomized controlled trials (RCTs) and three non-RCTs involving 1010 patients were enrolled in our meta-analysis. ThuEP provided less enucleation time when compared with HoLEP (WMD = - 7.73, 95% CI - 14.39-1.07, P = 0.02). During the 1st, 6th, and 12th months of postoperative follow-ups, statistically significant differences were found in Qmax (WMD = 2.05, 95% CI 0.52~3.58) and PVR (WMD = - 6.50, 95% CI - 7.35~- 5.66, P < 0.001) in the 1st month after the operation, also in IPSS (IPSS: WMD = - 1.29, 95% CI - 2.39~- 0.19, P = 0.02) in the 12th month after the operation. As regards other perioperative, postoperative parameters, and complication rates, we found no significant difference. Both ThuEP and HoLEP provided satisfactory micturition improvement with low morbidity after the 1st and 6th months of the operation. However, ThuEP showed higher enucleation efficacy and less intraoperative blood loss and may get a better outcome as compared to the HoLEP group in the early postoperative period with regard to Qmax/PVR and IPSS after the 1st and 12th months of the operation respectively.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.