ArticleInternational journal of clinical oncology2019
Risk factors for cardiovascular mortality in patients with colorectal cancer: a population-based study.
Article in International journal of clinical oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 38 citations in OpenAlex.
- Sex, Race and Ethnicity, and Rurality Disparities in Cardiovascular Death Among Adults With Early-Onset Colorectal Cancer: A Retrospective Cohort Analysis.Journal of the American Heart Association · 2026Article
- Risk of incident cardiovascular disease events among older Asian, Native Hawaiian, and Pacific Islander colorectal cancer survivors in the United States: a cohort study.Cardio-oncology (London, England) · 2026Article
- Association Between Surgery and Death from Cardiovascular Disease Among Patients with Laryngeal Cancer: A Large Population-Based Cohort Study.Annals of surgical oncology · 2025Article
- Neighborhood Disadvantage and Cardiovascular Mortality Among Colorectal Cancer Survivors.Cancers · 2025Article
- Subclinical Atherosclerosis and Cardiovascular Events Among Patients With Colorectal Cancer.Cancer medicine · 2025Article
- Major Adverse Cardiovascular Events After Colorectal Cancer Surgery, Oncological Outcomes, and Long-term Mortality: A Nationwide Retrospective Propensity Score-Matched Cohort Study.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2025Article
- Cardiovascular mortality risk among small bowel adenocarcinoma patients: a population-based study.BMC public health · 2025Article
- Cardiovascular Mortality Risk Among Patients with Liver Cancer: A SEER Database Study.Current cancer drug targets · 2025Article
- Health Literacy, Individual and Community Engagement, and Cardiovascular Risks and Disparities:JACC. CardioOncology · 2024Review
- Prognostic relevance of ventricular arrhythmias in surgical patients with gastrointestinal tumors.World journal of gastrointestinal oncology · 2024Article
- Cardiovascular mortality risk in patients with ovarian cancer: a population-based study.Journal of ovarian research · 2024Article
- Risk of cardiovascular death in patients with hepatocellular carcinoma based on the Fine-Gray model.World journal of gastrointestinal oncology · 2024Article
- Prevalence of traditional atherosclerotic risk factors in newly diagnosed colorectal and breast cancer patients.ARYA atherosclerosis · 2024Article
- Nomogram for predicting cardiovascular disease mortality in patients with meningioma: a competing risk analysis.Neurosurgical review · 2023Article
- The association of preoperative high-sensitivity cardiac troponin i and long-term outcomes in colorectal cancer patients received tumor resection surgery.Cardio-oncology (London, England) · 2023Article
- Incidence and risk factors of cardiovascular mortality in patients with gastrointestinal adenocarcinoma.PloS one · 2023Article
- Causes of death among early-onset colorectal cancer population in the United States: a large population-based study.Frontiers in oncology · 2023Article
- Cardiovascular Mortality Risk in Patients with Bladder Cancer: A Population-Based Study.Journal of cardiovascular development and disease · 2022Article
- Association of marital status with cardiovascular outcome in patients with breast cancer.Journal of thoracic disease · 2022Article
- Colorectal cancer surgery in elderly patients 80 years and older: a comparison with younger age groups.Journal of gastrointestinal oncology · 2022Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundPatients with colorectal cancer are at increased risk of cardiovascular mortality compared to the general population. The purpose of this study is to identify risk factors of cardiovascular mortality in patients with colorectal cancer.
methodsA retrospective review of the Surveillance Epidemiology and End Results (SEER) database was performed between 2010 and 2014. Standardized Mortality Ratios (SMRs) for cardiovascular mortality were calculated by comparing the number of expected deaths in the United States according to the National Center for Health Statistics (ICD-10 codes I00-I99) to the number of observed deaths in the database. Logistic regression was used to identify independent risk factors.
resultsOverall, 164,719 patients were identified (mean age at diagnosis 67 ± 13.9 years, 52.7% males, 47.3% females), of which 4854 (2.9%) died from cardiovascular disease. The majority of cardiovascular deaths occurred during the first year after diagnosis (2658, 54.8%). SMRs for cardiovascular mortality were 11.7 (95% CI 11.3-12) among all patients, 12.1 (95% CI 11.7-12.6) for male patients and 11.1 (95% CI 10.6-11.6) for female patients, with SMRs being higher for younger patients. Older age, male sex, African-American race, elevated CEA and not undergoing curative surgery were independent risk factors of cardiovascular mortality in patients with colorectal cancer.
conclusionPatients with colorectal cancer are associated with an increased risk of cardiovascular death, especially during the first year after diagnosis. Older age, male sex, African-American race, elevated CEA and not undergoing curative surgery are independent risk factors of cardiovascular death.
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