ArticleJournal of nephrology2019
How safe are organs from deceased donors with neoplasia? The results of the Italian Transplantation Network.
Article in Journal of nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Donor-transmitted cancer in kidney transplant recipients: a systematic review.Journal of nephrology · 2020Pooled it
- Impact of Thyroid Incidentaloma on Liver Transplant: A Study of 1010 Recipients at a Single Center.Annals of transplantation · 2022Trial
- Clinical management of cancer after kidney transplantation.Frontiers in immunology · 2026Review
- ISOT position statement on the feasibility of an organ for transplantation from brain-dead deceased donors: a Delphi consensus.The Lancet regional health. Southeast Asia · 2025Review
- Donors With Previous Malignancy: When Is It Safe to Proceed With Organ Transplantation?Transplant international : official journal of the European Society for Organ Transplantation · 2025Review
- Retrospective assessment of the frequency of cancer in the population of kidney transplant recipients - the experience of two transplant centers.Frontiers in oncology · 2025Article
- Aggressive variant prostate cancer: A case report and literature review.World journal of clinical cases · 2023Article
- Second Opinion in the Italian Organ Procurement Transplantation: The Pathologist Is In.Clinics and practice · 2023Article
- Critical Evaluation of Discarded Donor Livers in the Eurotransplant Region: Potential Implications for Machine Perfusion.Annals of transplantation · 2023Article
- Shared decision-making and disclosure of adverse events: critical aspects for the quality and safety of kidney transplant practice.Journal of nephrology · 2022Article
- Validation of portable tablets for transplant pathology diagnosis according to the College of American Pathologists Guidelines.Academic pathology · 2022Article
- The 3-T Model of Informed Consent for Nonstandard Risk Donors: A Proposal for Transplant Clinical Practice.Transplantation direct · 2021Article
- Diffuse Micro-Nodules on Peritoneal Surfaces at Donor Organ Procurement: Highlights on the Diagnostic Challenge and Transplant Management.The American journal of case reports · 2021Article
- A sticky, palpable area of the perinephric adipose tissue at organ donor procurement: highlights on the diagnostic challenge and transplant management.Journal of nephrology · 2020Article
Corrections and comments
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Authors and funding
16 authors at 7 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Guidelines for donor selection have changed to expand the donor pool, considering potential donors affected by a neoplasm. Aim of this retrospective study is to look at the use of organs from donors with a current or history of neoplasm within the Italian Transplant Network. Data, collected and validated by Italian National Health Institute for the time interval 2006-2015, have been reviewed retrospectively by mean of multivariable pivot tables. Donors with neoplasia represented about 5% of all donors, resulting in about 4% of all transplants. Donors presented a benign neoplasm in 29.08% of cases, a malignancy with variable risk of transmission in 69.75% while in 1.34% the nature of neoplasm could not be assessed. Considering all procedures, rate of transmission of a malignancy was 0.03% (10 cases) of all 29858 transplants of the time interval. Notably, cases of transmission were not from donors of this pool, but from donors that, according to our protocols, had no elements of suspect at time of donation. As recipient safety is always the priority and as guidelines have set exclusion criteria for donors with some specific types of malignancy, these results show that use of this type of donors is safe and improve organ pool. Furthermore represent basis for improvement and standardization of donor assessment protocols suggesting that efforts in data collection systems, to produce complete and homogeneous data, are mandatory.
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