Evidence map›Paper›PMID 30603981›Full record

ArticleNeurochemical research2019

Electroacupuncture and Curcumin Promote Oxidative Balance and Motor Function Recovery in Rats Following Traumatic Spinal Cord Injury.

Belen G Alvarado-Sanchez, Hermelinda Salgado-Ceballos, Sergio Torres-Castillo, Juan Rodriguez-Silverio, Monica E Lopez-Hernandez, Salvador Quiroz-Gonzalez, Stephanie Sanchez-Torres, Rodrigo Mondragón-Lozano, Omar Fabela-Sanchez

Abstract read
PubMed Publisher
In one paragraph

Article in Neurochemical research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Belen G Alvarado-SanchezEscuela Superior de Medicina, Instituto Politécnico Nacional, C.P. 11340, México City, Mexico.
Hermelinda Salgado-CeballosUnidad de Investigación Médica en Enfermedades Neurológicas, Centro Médico Nacional Siglo XXI, IMSS, C.P. 06720, México City, Mexico.
Sergio Torres-CastilloUniversidad Estatal del Valle de Ecatepec, C.P. 55210, Ecatepec de Morelos, Estado De México, Mexico. sergio_torresc@yahoo.com.
Juan Rodriguez-SilverioEscuela Superior de Medicina, Instituto Politécnico Nacional, C.P. 11340, México City, Mexico.
Monica E Lopez-HernandezUniversidad Estatal del Valle de Ecatepec, C.P. 55210, Ecatepec de Morelos, Estado De México, Mexico.
Salvador Quiroz-GonzalezUniversidad Estatal del Valle de Ecatepec, C.P. 55210, Ecatepec de Morelos, Estado De México, Mexico.
Stephanie Sanchez-TorresUAM Iztapalapa, C.P. 09340, México City, Mexico.
Rodrigo Mondragón-LozanoUnidad de Investigación Médica en Enfermedades Neurológicas, Centro Médico Nacional Siglo XXI, IMSS, C.P. 06720, México City, Mexico.
Omar Fabela-SanchezUAM Iztapalapa, C.P. 09340, México City, Mexico.
Universidad Estatal del Valle de Ecatepec · MXCentro Medico Nacional Siglo XXI · MXInstituto Politécnico Nacional · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spinal cord injury (SCI) is a condition that puts the patient's life at risk in the acute phase and, during the chronic stage, results in permanent deficits in motor, sensory and autonomic functions. Isolated therapeutic strategies have not shown an effect on this condition. Therefore, this study aimed to evaluate the effects of electroacupuncture (EA) and curcumin, alone or combined, on the oxidative balance, motor function recovery and amount of preserved tissue following a traumatic SCI. Long-Evans rats were divided into five groups: SHAM, SCI, SCI + EA, SCI + Curcumin, and SCI + EA + Curcumin. Nitric oxide was significantly decreased in the Curcumin group; the EA, Curcumin and SCI + EA + Curcumin groups had significantly decreased hydroxyl radical and lipid peroxidation levels. Motor function recovery and the amount of preserved spinal cord tissue were significantly greater in the EA, Curcumin and EA + Curcumin groups. The results show that EA and Curcumin treatment alone or in combination decreased oxidative stress, improved functional motor recovery and increased the amount of preserved spinal cord tissue following a traumatic injury.

Indexed as

ElectroacupunctureAnimalsCurcuminDisease Models, AnimalFemaleLipid PeroxidationOxidative StressRats, Long-EvansRecovery of FunctionSpinal CordSpinal Cord InjuriesCurcuminCurcuminElectroacupunctureLipid peroxidationMotor function recoveryOxidative stressSpinal cord injury

Identifiers

PMID30603981
OpenAlexW2907562298

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.