Evidence map›Paper›PMID 30603897›Full record

ArticleJournal of medical toxicology : official journal of the American College of Medical Toxicology2019

Poor Identification of Emergency Department Acute Recreational Drug Toxicity Presentations Using Routine Hospital Coding Systems: the Experience in Denmark, Switzerland and the UK.

David M Wood, Luke De La Rue, Ali A Hosin, Gesche Jurgens, Evangelia Liakoni, Fritdjof Heyerdahl, Knut Erik Hovda, Alison Dines, Isabelle Giraudon, Matthias E Liechti and 1 more

Abstract read
In one paragraph

Article in Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

David M WoodClinical Toxicology, Guy's and St Thomas' NHS Foundation Trust and King's Health Partners, St Thomas' Hospital, 3rd Floor, Block C, South Wing, Westminster Bridge Road, London, SE1 7EH, UK. David.Wood@gstt.nhs.uk.ORCID 0000-0002-7826-7237
Luke De La RueClinical Toxicology, Guy's and St Thomas' NHS Foundation Trust and King's Health Partners, St Thomas' Hospital, 3rd Floor, Block C, South Wing, Westminster Bridge Road, London, SE1 7EH, UK.
Ali A HosinGeneral Medicine, University College Hospital London, 235 Euston Rd, Fitzrovia, London, NW1 2BU, UK.
Gesche JurgensClinical Pharmacology Unit, Zealand University Hospital, Sygehusvej 10, 4000, Roskilde, Denmark.
Evangelia LiakoniDivision of Clinical Pharmacology and Toxicology, Basel University Hospital, Spitalstrasse 21, 4031, Basel, Switzerland.
Fritdjof HeyerdahlThe Norwegian CBRNE Centre of Medicine, Department of Acute Medicine, Ullevål Hospital, Kirkeveien 166, 0450, Oslo, Norway.
Knut Erik HovdaThe Norwegian CBRNE Centre of Medicine, Department of Acute Medicine, Ullevål Hospital, Kirkeveien 166, 0450, Oslo, Norway.
Alison DinesClinical Toxicology, Guy's and St Thomas' NHS Foundation Trust and King's Health Partners, St Thomas' Hospital, 3rd Floor, Block C, South Wing, Westminster Bridge Road, London, SE1 7EH, UK.
Isabelle GiraudonRisks to public safety and security unit, European Monitoring Centre for Drugs and Drug Addiction (EMCDDA), Praça Europa 1, Cais do Sodré, 1249-289, Lisbon, Portugal.
Matthias E LiechtiDivision of Clinical Pharmacology and Toxicology, Basel University Hospital, Spitalstrasse 21, 4031, Basel, Switzerland.
Paul I DarganClinical Toxicology, Guy's and St Thomas' NHS Foundation Trust and King's Health Partners, St Thomas' Hospital, 3rd Floor, Block C, South Wing, Westminster Bridge Road, London, SE1 7EH, UK.

Funding

European Monitoring Centre for Drugs and Drug Addiction N/Athe DPIP/ISEC Programme of the European Union N/A
6 · The paper itself

Abstract

backgroundUnderstanding emergency department and healthcare utilisation related to acute recreational drug toxicity (ARDT) generally relies on nationally collated data based on ICD-10 coding. Previous UK studies have shown this poorly captures the true ARDT burden. The aim of this study was to investigate whether this is also the case elsewhere in Europe.

methodsThe Euro-DEN Plus database was interrogated for all presentations 1st July to 31st December 2015 to the EDs in (i) St Thomas' Hospital, London, UK; (ii) Universitätsspital Basel, Basel, Switzerland; and (iii) Zealand University Hospital, Roskilde, Denmark. Comparison of the drug(s) involved in the presentation with the ICD-10 codes applied to those presentations was undertaken to determine the proportion of cases where the primary/subsequent ICD-10 code(s) were ARDT related.

resultsThere were 619 presentations over the 6-month period. Two hundred thirteen (34.4%) of those presentations were coded; 89.7% had a primary/subsequent ARDT-related ICD-10 code. One hundred percent of presentations to Roskilde had a primary ARDT ICD-10 code compared to 9.6% and 18.9% in Basel and London respectively. Overall, only 8.5% of the coded presentations had codes that captured all of the drugs that were involved in that presentation.

conclusionsWhile the majority of primary and secondary codes applied related to ARDT, often they did not identify the actual drug(s) involved. This was due to both inconsistencies in the ICD-10 codes applied and lack of ICD-10 codes for the drugs/NPS. Further work and education is needed to improve consistency of use of current ICD-10 and future potential ICD-11 coding systems.

Indexed as

Emergency Service, HospitalAnalgesics, OpioidCannabisCocaineDatabases, FactualDenmarkDrug OverdoseEmergency Medical ServicesHumansIllicit DrugsInternational Classification of DiseasesMethamphetamineSwitzerlandUnited KingdomAnalgesics, OpioidCocaineIllicit DrugsmephedroneMethamphetamineAcute toxicityClinical codingEmergency departmentNovel psychoactive substancesRecreational drugs

Identifiers

PMID30603897
PMCPMC6440929

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.