ReviewTissue engineering and regenerative medicine2018
Injectable Biomaterials in Plastic and Reconstructive Surgery: A Review of the Current Status.
Review in Tissue engineering and regenerative medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Adipose Tissue-derived Stem cells in Plastic and Reconstructive Surgery: A Bibliometric Study.Aesthetic plastic surgery · 2021Pooled it
- Reconstruction of midface defects using local flaps: An algorithm for appropriate flap choice.Medicine · 2019Trial
- Regenerative Functional Microspheres for Aesthetic Medicine: Mechanism, Materials, Fabrication, and Clinical Applications.Advanced healthcare materials · 2026Review
- Recent Advances in Injectable Hydrogels for Biomedical and Aesthetic Applications: Focus on Rheological Characteristics.Gels (Basel, Switzerland) · 2025Review
- Facial Injectable Fillers in Aesthetic Medicine: Clinical Applications and Safety Strategies.Medical science monitor : international medical journal of experimental and clinical research · 2025Review
- Collagen Use in Periorbital Rejuvenation for Chinese Patients: The Restoration Injection for Optimal Rejuvenation Technique.Plastic and reconstructive surgery. Global open · 2025Article
- Preparation and Characterization of Injectable Augmentation Gels Containing Polycaprolactone and Hyaluronic Acid.Journal of cosmetic dermatology · 2025Article
- Recombinant human collagen type III microgel: an advanced injectable dermal filler for rejuvenating aging skin.Regenerative biomaterials · 2025Article
- Collagen-Based Medical Devices for Regenerative Medicine and Tissue Engineering.Applied biochemistry and biotechnology · 2024Review
- Evaluation of Collagen Dermal Filler with Lidocaine for the Correction of Nasolabial Folds: A Randomized, Double-Blind, Multicenter Clinical Trial.Clinical, cosmetic and investigational dermatology · 2024Article
- An Update on the Clinical Efficacy and Safety of Collagen Injectables for Aesthetic and Regenerative Medicine Applications.Polymers · 2023Review
- Application of 3D-printed tissue-engineered skin substitute using innovative biomaterial loaded with human adipose-derived stem cells in wound healing.International journal of bioprinting · 2023Article
- Review of Plastic Surgery Biomaterials and Current Progress in Their 3D Manufacturing Technology.Materials (Basel, Switzerland) · 2020Review
- Optimal Condition of Isolation from an Adipose Tissue-Derived Stromal Vascular Fraction for the Development of Automated Systems.Tissue engineering and regenerative medicine · 2020Article
- Engineering 3D degradable, pliable scaffolds toward adipose tissue regeneration; optimized printability, simulations and surface modification.Journal of tissue engineeringArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInjectable biomaterials have attracted increasing attention for volume restoration and tissue regeneration. The main aim of this review is to discuss the current status of the injectable biomaterials for correction of tissue defects in plastic and reconstructive surgery.
methodsRequirements of injectable biomaterials, mechanism of in situ gelation, characteristics, and the combinational usage of adipose-derived stem cells (ADSCs) and growth factors were reviewed.
resultsThe ideal injectable biomaterials should be biocompatible, non-toxic, easy to use, and cost-effective. Additionally, it should possess adequate mechanical properties and stability. In situ gelation method includes physical, chemical, enzymatic and photo-initiated methods. Natural and synthetic biomaterials carry their pros and cons due to their inherent properties. The combined use of ADSCs and growth factors provides enhanced potential for adipose tissue regeneration.
conclusionsThe usage of injectable biomaterials has been increasing for the tissue restoration and regeneration. The future of incorporating ADSCs and growth factors into the injectable biomaterials is promising.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.