ArticleTissue engineering and regenerative medicine2018
Osteogenic Nanofibrous Coated Titanium Implant Results in Enhanced Osseointegration:
Article in Tissue engineering and regenerative medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed.
- Effect of Rare-Earth Element Microdoping on Ti-6Al-7Nb Alloys for Biomedical Applications: Materials Characterization and In Vivo Biocompatibility Tests.Materials (Basel, Switzerland) · 2026Article
- Sustained release of Sr and Ca from a micronanotopographic titanium surface improves osteoblast function.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025Article
- The Effects of Statins on Bone Formation Around Implants Placed in Animal Bones: A Systematic Review and Meta-Analysis.Journal of maxillofacial and oral surgery · 2023Review
- X-ray computed microtomography datasets for osteogenic nanofibrous coated titanium implants.Scientific data · 2022Article
- Fluorine-incorporated TiOJournal of biomedical materials research. Part A · 2021Article
- Enhancing Osseointegration of TC4 Alloy by Surficial Activation Through Biomineralization Method.Frontiers in bioengineering and biotechnology · 2021Article
- Current Insight of Collagen Biomatrix for Gingival Recession: An Evidence-Based Systematic Review.Polymers · 2020Review
- Accentuated osseointegration in osteogenic nanofibrous coated titanium implants.Scientific reports · 2019Article
- Near-Infrared Contrast Agents for Bone-Targeted Imaging.Tissue engineering and regenerative medicine · 2019Review
- Urine Aluminum Concentration as a Possible Implant Biomarker ofACS omega · 2019Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A titanium implant surface when coated with biodegradable, highly porous, osteogenic nanofibrous coating has shown enhanced intrinsic osteoinductive and osteoconductive properties. This coating mimics extracellular matrix resulting in differentiation of stem cells present in the peri-implant niche to osteoblast and hence results in enhanced osseointegration of the implant. The osteogenic nanofibrous coating (ONFC) consists of poly-caprolactone, gelatin, nano-sized hydroxyapatite, dexamethasone, ascorbic acid and beta-glycerophosphate. ONFC exhibits optimum mechanical properties to support mesenchymal stem cells and steer their osteogenic differentiation. ONFC was subjected to various characterization tests like scanning electron microscopy, Fourier-transform infrared spectroscopy, x-ray diffractometry, thermal degradation, biomineralization, mechanical properties, wettability and proliferation assay. In pre-clinical animal trials, the coated implant showed enhanced new bone formation when placed in the tibia of rabbit. This novel approach toward implant bone integration holds significant promise for its easy and economical coating thus marking the beginning of new era of electrospun osteogenic nanofibrous coated bone implants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.