Evidence map›Paper›PMID 30603531›Full record

ArticleTissue engineering and regenerative medicine2018

Synergistic Effect of Cold Plasma Treatment and RGD Peptide Coating on Cell Proliferation over Titanium Surfaces.

Ozan Karaman, Seyfi Kelebek, Emine Afra Demirci, Fatma İbiş, Murat Ulu, Utku Kürşat Ercan

Abstract read
In one paragraph

Article in Tissue engineering and regenerative medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ozan Karaman1Tissue Engineering and Regenerative Medicine Laboratory, Department of Biomedical Engineering, Faculty of Engineering and Architecture, Rm 148, İzmir Katip Çelebi University, 35620 İzmir, Turkey.ORCID 0000-0002-4175-4402
Seyfi Kelebek2Department of Oral and Maxillofacial Surgery, İzmir Katip Çelebi University, 35620 İzmir, Turkey.
Emine Afra Demirci1Tissue Engineering and Regenerative Medicine Laboratory, Department of Biomedical Engineering, Faculty of Engineering and Architecture, Rm 148, İzmir Katip Çelebi University, 35620 İzmir, Turkey.
Fatma İbiş3Plasma Medicine Laboratory, Department of Biomedical Engineering, Faculty of Engineering and Architecture, Rm 123, İzmir Katip Çelebi University, 35620 İzmir, Turkey.
Murat Ulu2Department of Oral and Maxillofacial Surgery, İzmir Katip Çelebi University, 35620 İzmir, Turkey.
Utku Kürşat Ercan3Plasma Medicine Laboratory, Department of Biomedical Engineering, Faculty of Engineering and Architecture, Rm 123, İzmir Katip Çelebi University, 35620 İzmir, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to investigate the synergistic effect of cold atmospheric plasma (CAP) treatment and RGD peptide coating for enhancing cellular attachment and proliferation over titanium (Ti) surfaces. The surface structure of CAP-treated and RGD peptide-coated Ti discs were characterized by contact angle goniometer and atomic force microscopy. The effect of such surface modification on human bone marrow derived mesenchymal stem cells (hMSCs) adhesion and proliferation was assessed by cell proliferation and DNA content assays. Besides, hMSCs' adhesion and morphology on surface modified Ti discs were observed via fluorescent and scanning electron microscopy. RGD peptide coating following CAP treatment significantly enhanced cellular adhesion and proliferation among untreated, CAP-treated and RGD peptide-coated Ti discs. The treatment of Ti surfaces with CAP may contribute to improved RGD peptide coating, which enables increased cellular integrations with the Ti surfaces.

Indexed as

Cell adhesion and proliferationNon-thermal atmospheric plasmaRGD peptideSurface modificationTitanium dental implants

Identifiers

PMID30603531
PMCPMC6171635

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.