ArticleTissue engineering and regenerative medicine2017
Novel Approach Toward the Generation of Tissue Engineered Heart Valve by Using Combination of Antioxidant and Detergent: A Potential Therapy in Cardiovascular Tissue Engineering.
Article in Tissue engineering and regenerative medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Decellularized small intestine scaffolds: a potential xenograft for restoration of intestinal perforation.Tissue barriers · 2024Article
- Characterization and angiogenic potential of CD146Stem cell research & therapy · 2024Article
- Recellularization of Acellular Xeno Kidney Scaffold: An In Vivo Method to Generate Bioartificial Kidney.Advances in experimental medicine and biology · 2024Article
- Heparin coated decellularized xenogeneic small diameter vascular conduit for vascular repair with early luminal reendothelialization.Cell and tissue banking · 2023Article
- Heparin Immobilization of Tissue Engineered Xenogeneic Small Diameter Arterial Scaffold Improve Endothelialization.Tissue engineering and regenerative medicine · 2022Article
- Tissue engineered human ear pinna derived from decellularized goat ear cartilage: clinically useful and biocompatible auricle construct.Cell and tissue banking · 2022Article
- Heart valve mechanical prosthesis: The perfect match until it is not - A case report.Experimental and therapeutic medicine · 2020Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To develop decellularized heart valve scaffold from porcine for heart valve regeneration. Porcine heart valves were decellularized with unique optimized approach by using 1% sodium dodecyl sulfate solution and 5% dimethyl sulfoxide for the first time. Effect of decellularization process on scaffold were characterized by hematoxylin-eosin, 4',6-diamidino-2-phenylindole, Masson's trichrome, alcian blue staining and scanning electron microscopy for extracellular matrix (ECM) analysis in scaffold. The results showed that developed protocol for decellularization of heart valve scaffold shown complete removal of all cellular components, without changing the properties of ECM. The developed protocol was successfully used for heart valve ECM scaffolds development from porcine. The developed protocol seems to be promising solution for the heart valve tissue engineering application.
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Registered trials
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