Evidence map›Paper›PMID 30603492›Full record

ArticleTissue engineering and regenerative medicine2017

Surface Coating of Polytetrafluoroethylene with Extracellular Matrix and Anti-CD34 Antibodies Facilitates Endothelialization and Inhibits Platelet Adhesion Under Sheer Stress.

Lei Chen, Haipeng He, Mian Wang, Xiaoxi Li, Henghui Yin

Open access · bronzeAbstract read
In one paragraph

Article in Tissue engineering and regenerative medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Lei Chen1Department of Vascular Surgery, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510080 China.
Haipeng He2Department of Vascular Surgery, The First Affiliated Hospital of Ji'nan University, Guangzhou, 510630 China.
Mian Wang1Department of Vascular Surgery, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510080 China.
Xiaoxi Li1Department of Vascular Surgery, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510080 China.
Henghui Yin3Department of Vascular Surgery, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080 China.
The First Affiliated Hospital, Sun Yat-sen University · CNFirst Affiliated Hospital of Jinan University · CNSun Yat-sen University · CNThird Affiliated Hospital of Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Expanded polytetrafluoroethylene (ePTFE) polymers do not support endothelialization because of nonconductive characteristics towards cellular attachment. Inner surface modification of the grafts can improve endothelialization and increase the long-term patency rate of the ePTFE vascular grafts. Here we reported a method of inner-surface modification of ePTFE vascular graft with extracellular matrix (ECM) and CD34 monoclonal antibodies (CD34 mAb) to stimulate the adhesion and proliferation of circulating endothelial progenitor cells on ePTFE graft to enhance graft endothelialization. The inner surface of ECM-coated ePTFE grafts were linked with CD34 mAb in the presence of 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide/

Indexed as

Anti-CD34 antibodyEDC/NHS solutionEndothelial cellsePTFE vascular graftsExtracellular matrix

Identifiers

PMID30603492
PMCPMC6171604
OpenAlexW2591833311

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.