ArticleTissue engineering and regenerative medicine2017
Intra-articular Xenotransplantation of Adipose-Derived Stromal Cells to Treat Osteoarthritis in a Goat Model.
Article in Tissue engineering and regenerative medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 20 citations in OpenAlex.
- Materiobiology-guided regulation of mesenchymal stromal cell fate for aging-related diseases: From basic parameter design to clinical application.Bioactive materials · 2026Review
- Bioengineered chondrocyte-products from human induced pluripotent stem cells are useful for repairing articular cartilage injury in minipig model.NPJ Regenerative medicine · 2025Article
- Mesenchymal Stem Cell Studies in the Goat Model for Biomedical Research-A Review of the Scientific Literature.Biology · 2022Review
- In utero xenotransplantation of mice bone marrow-derived stromal/stem cells into fetal rat liver: An experimental study.International journal of reproductive biomedicine · 2020Article
- Genome Engineering for Osteoarthritis: From Designer Cells to Disease-Modifying Drugs.Tissue engineering and regenerative medicine · 2019Review
- Perspective on Intra-articular Injection Cell Therapy for Osteoarthritis Treatment.Tissue engineering and regenerative medicine · 2019Review
- Updates in Cartilage Tissue Regeneration.Tissue engineering and regenerative medicine · 2019Article
- Adipose Stem Cells with Conditioned Media for Treatment of Acne Vulgaris Scar.Tissue engineering and regenerative medicine · 2018Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adipose-derived stromal cells (ASCs) have been investigated as a cell source for tissue regeneration. The purpose of this study was first to confirm if medial meniscectomy induces osteoarthritis (OA) in goats within a relative short period of time, and more importantly, to investigate if systemic treatment with immunosuppressive drugs is necessary in intra-articular ASC xenotransplantation for successful regeneration of articular cartilage and prevention of joint inflammation. Eight Korean native black goats 1-2 years of age underwent medial meniscectomy. To evaluate the gross and histological appearance of articular cartilage, knee joints were re-exposed by a medial parapatellar incision at 8 weeks. After macroscopic scoring of gross appearance, cartilage biopsy specimens 6 mm in diameter were obtained from the femoral condyle in four goats. The goats were injected with single intra-articular dose of 7×10
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